SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
3 / 3 ARG A 155
ARG A 165
PRO A 153
None
0.96A 2wljA-1zboA:
undetectable
2wljA-1zboA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_C_TMQC202_1
(DIHYDROFOLATE
REDUCTASE)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
5 / 12 ALA A 198
LEU A 172
PRO A 173
LEU A 180
ILE A 192
None
1.01A 4m2xC-1zboA:
undetectable
4m2xC-1zboA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
5 / 12 ALA A 198
LEU A 172
PRO A 173
LEU A 180
ILE A 192
None
1.09A 4m2xE-1zboA:
undetectable
4m2xE-1zboA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
3 / 3 GLU A  60
TYR A  28
GLU A  25
None
0.82A 4ryaA-1zboA:
undetectable
4ryaA-1zboA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
3 / 3 ARG A  27
GLN A  99
GLU A  60
None
0.93A 4tvtA-1zboA:
undetectable
4tvtA-1zboA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
3 / 3 ASP A 158
ARG A 188
PRO A 185
None
0.86A 4wanC-1zboA:
undetectable
4wanC-1zboA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
3 / 3 ASP A 115
GLY A 160
ASP A 158
None
0.69A 4xdtA-1zboA:
undetectable
4xdtA-1zboA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)
1zbo HYPOTHETICAL PROTEIN
BPP1347

(Bordetella
parapertussis)
4 / 5 TRP A 105
LEU A   6
VAL A  45
LEU A  94
None
0.88A 5xooB-1zboA:
undetectable
5xooB-1zboA:
21.34