SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1zc3 EXOCYST COMPLEX
PROTEIN EXO84
(Rattus
norvegicus) 		4 / 7 LEU B 268
VAL B 267
TYR B 176
LEU B 180
 None
 0.81A 1cqpA-1zc3B:
undetectable
1cqpB-1zc3B:
undetectable		 1cqpA-1zc3B:
19.46
1cqpB-1zc3B:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1zc3 EXOCYST COMPLEX
PROTEIN EXO84
(Rattus
norvegicus) 		4 / 8 TYR B 176
ILE B 260
LEU B 268
PHE B 242
 None
 1.01A 3rqwI-1zc3B:
undetectable
3rqwJ-1zc3B:
undetectable		 3rqwI-1zc3B:
17.69
3rqwJ-1zc3B:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 1zc3 EXOCYST COMPLEX
PROTEIN EXO84
(Rattus
norvegicus) 		5 / 10 PHE B 253
ILE B 252
ASP B 234
ASN B 231
MET B 238
 None
 1.39A 6r2eC-1zc3B:
0.0		 6r2eC-1zc3B:
15.90