SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zc4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 1zc4 RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 4 SER A 100
SER A  22
LEU A 124
PHE A 107
 None
 1.22A 1r5lA-1zc4A:
0.8		 1r5lA-1zc4A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1zc4 RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		5 / 12 THR A  46
GLY A  26
GLY A  24
GLY A  71
ASP A 130
 MG  A 200 ( 2.7A)
GNP  A 400 (-3.2A)
GNP  A 400 (-3.4A)
GNP  A 400 (-3.6A)
GNP  A 400 (-2.9A)
 1.01A 2b25A-1zc4A:
undetectable		 2b25A-1zc4A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 1zc4 RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 5 ALA A 177
GLY A  88
LYS A  16
HIS A  15
 None
 1.32A 2ylgA-1zc4A:
undetectable		 2ylgA-1zc4A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1zc4 RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 8 GLY A  21
VAL A  92
PHE A  83
ILE A  18
 None
 0.79A 4fglD-1zc4A:
4.6		 4fglD-1zc4A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1zc4 RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 7 GLY A  21
VAL A  92
PHE A  83
ILE A  18
 None
 0.80A 4fglC-1zc4A:
4.7		 4fglC-1zc4A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 1zc4 RAS-RELATED PROTEIN
RAL-A
(Homo
sapiens) 		4 / 5 ALA A 177
GLY A  88
LYS A  16
HIS A  15
 None
 1.29A 5jliA-1zc4A:
undetectable		 5jliA-1zc4A:
23.73