SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 ASN A  17
THR A  57
TRP A  79
ASP A  50
 None
 0.97A 1bu5A-1zccA:
undetectable		 1bu5A-1zccA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ASN A  17
THR A  57
TRP A  79
ASP A  50
 None
 0.98A 1bu5B-1zccA:
undetectable		 1bu5B-1zccA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 7 GLU A 108
LEU A 109
VAL A 117
LEU A  96
 SO4  A4770 ( 3.7A)
None
None
None
 1.03A 1hk3A-1zccA:
undetectable		 1hk3A-1zccA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 12 ASP A 226
ILE A   4
ILE A 220
GLY A 202
ALA A  25
 None
 0.98A 1sguB-1zccA:
undetectable		 1sguB-1zccA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 10 ASP A 226
ILE A   4
ILE A 220
GLY A 202
ALA A  25
 None
 1.07A 1sh9B-1zccA:
undetectable		 1sh9B-1zccA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 6 PHE A  19
VAL A  47
LEU A  35
ALA A  22
 None
 1.01A 2e1qA-1zccA:
undetectable		 2e1qA-1zccA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 6 PHE A  19
VAL A  47
LEU A  35
ALA A  22
 None
 1.00A 2e1qC-1zccA:
undetectable		 2e1qC-1zccA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		6 / 12 LEU A  24
GLY A  29
ALA A  30
ASP A  31
ILE A  33
ALA A  21
 None
 1.38A 2rkfB-1zccA:
undetectable		 2rkfB-1zccA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		3 / 3 GLU A 108
HIS A   7
GLU A  34
 SO4  A4770 ( 3.7A)
SO4  A4770 (-4.2A)
None
 0.65A 2x45B-1zccA:
undetectable		 2x45B-1zccA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		3 / 3 GLU A 108
HIS A   7
GLU A  34
 SO4  A4770 ( 3.7A)
SO4  A4770 (-4.2A)
None
 0.65A 2x45C-1zccA:
undetectable		 2x45C-1zccA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 ILE A 146
PRO A 114
GLY A 142
SER A 134
 None
 0.95A 3lslA-1zccA:
undetectable
3lslD-1zccA:
undetectable		 3lslA-1zccA:
22.30
3lslD-1zccA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID801_0
(GLUTAMATE RECEPTOR 2)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 8 SER A 134
ILE A 146
PRO A 114
GLY A 142
 None
 0.91A 3lslA-1zccA:
undetectable
3lslD-1zccA:
undetectable		 3lslA-1zccA:
22.30
3lslD-1zccA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 12 PHE A  84
GLY A  78
ALA A  10
GLY A   9
GLN A  27
 None
 1.02A 3v3oA-1zccA:
undetectable		 3v3oA-1zccA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 12 LEU A  35
ALA A  22
ILE A 107
GLY A 104
ALA A 103
 None
 1.05A 4nkvA-1zccA:
undetectable		 4nkvA-1zccA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 12 LEU A  35
ALA A  22
ILE A 107
GLY A 104
ALA A 103
 None
 1.04A 4nkvC-1zccA:
undetectable		 4nkvC-1zccA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		5 / 12 LEU A  35
ALA A  22
ILE A 107
GLY A 104
ALA A 103
 None
 1.05A 4nkvD-1zccA:
undetectable		 4nkvD-1zccA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 4 LEU A 222
ASP A 226
PRO A 225
ARG A 224
 None
 1.20A 6fgdA-1zccA:
2.2		 6fgdA-1zccA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE
(Agrobacterium
fabrum) 		4 / 6 TYR A 106
GLU A 108
ASP A  36
GLU A  16
 None
SO4  A4770 ( 3.7A)
SO4  A4770 ( 4.1A)
None
 1.48A 6mn5A-1zccA:
undetectable		 6mn5A-1zccA:
15.83