SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zcl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		5 / 9 PHE A  92
LEU A 119
ILE A  21
VAL A 102
ILE A 100
 None
 1.36A 1gebA-1zclA:
undetectable		 1gebA-1zclA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		5 / 9 PHE A  92
VAL A  12
ILE A  21
VAL A 102
ILE A 100
 None
 1.34A 1gebA-1zclA:
undetectable		 1gebA-1zclA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		4 / 7 ASN A  24
TYR A  53
ASN A  27
VAL A  58
 None
 1.28A 1wu8A-1zclA:
undetectable
1wu8C-1zclA:
undetectable		 1wu8A-1zclA:
21.67
1wu8C-1zclA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		4 / 5 PRO A 112
VAL A 115
VAL A  12
ILE A  21
 None
 0.79A 1z2bC-1zclA:
undetectable		 1z2bC-1zclA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		3 / 3 ASP A  72
LEU A 108
GLY A 109
 SO4  A4398 (-4.1A)
SO4  A4398 (-4.2A)
SO4  A4398 (-3.1A)
 0.57A 4xmfA-1zclA:
undetectable		 4xmfA-1zclA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		4 / 7 PRO A 112
VAL A 115
VAL A  12
ILE A  21
 None
 0.64A 5bmvC-1zclA:
undetectable		 5bmvC-1zclA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 1zcl PROTEIN TYROSINE
PHOSPHATASE 4A1
(Rattus
norvegicus) 		4 / 8 LEU A 146
LEU A 149
LEU A 108
GLY A 107
 None
None
SO4  A4398 (-4.2A)
SO4  A4398 (-3.4A)
 0.77A 6ce2A-1zclA:
undetectable		 6ce2A-1zclA:
20.90