SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M9Q_B_BEZB251_0 (SERINE PROTEASE INHIBITOR SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3)	1zd0	HYPOTHETICAL PROTEIN PF0523 (Pyrococcus furiosus)	5 / 9	ILE A 20 THR A 56 VAL A 104 THR A 105 ALA A 110	None	1.17A	2m9qA-1zd0A: undetectable	2m9qA-1zd0A: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNJ_A_CHDA501_0 (FERROCHELATASE, MITOCHONDRIAL)	1zd0	HYPOTHETICAL PROTEIN PF0523 (Pyrococcus furiosus)	5 / 12	LEU A 118 LEU A 114 ILE A 123 PRO A 74 VAL A 73	None	1.13A	2pnjA-1zd0A: undetectable	2pnjA-1zd0A: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_G_Z80G401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	1zd0	HYPOTHETICAL PROTEIN PF0523 (Pyrococcus furiosus)	5 / 10	ILE A 103 ILE A 123 VAL A 43 GLU A 98 ILE A 30	None None None UNX A 406 ( 4.4A) None	1.29A	5lg3G-1zd0A: undetectable	5lg3G-1zd0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_H_Z80H401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	1zd0	HYPOTHETICAL PROTEIN PF0523 (Pyrococcus furiosus)	5 / 10	ILE A 103 ILE A 123 VAL A 43 GLU A 98 ILE A 30	None None None UNX A 406 ( 4.4A) None	1.26A	5lg3H-1zd0A: undetectable	5lg3H-1zd0A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J20_A_GBQA1201_1 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	1zd0	HYPOTHETICAL PROTEIN PF0523 (Pyrococcus furiosus)	4 / 7	ILE A 123 GLN A 29 GLU A 98 VAL A 23	None None UNX A 406 ( 4.4A) None	0.78A	6j20A-1zd0A: undetectable	6j20A-1zd0A: 15.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2M9Q_B_BEZB251_0","SERINE PROTEASE INHIBITOR;SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3","1zd0","HYPOTHETICAL PROTEIN PF0523","Pyrococcus furiosus",5,"ILE A  20;THR A  56;VAL A 104;THR A 105;ALA A 110","None","1.17A","2m9qA-1zd0A:undetectable","2m9qA-1zd0A:25.00"],["2PNJ_A_CHDA501_0","FERROCHELATASE, MITOCHONDRIAL","1zd0","HYPOTHETICAL PROTEIN PF0523","Pyrococcus furiosus",5,"LEU A 118;LEU A 114;ILE A 123;PRO A  74;VAL A  73","None","1.13A","2pnjA-1zd0A:undetectable","2pnjA-1zd0A:16.90"],["5LG3_G_Z80G401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","1zd0","HYPOTHETICAL PROTEIN PF0523","Pyrococcus furiosus",5,"ILE A 103;ILE A 123;VAL A  43;GLU A  98;ILE A  30","None;None;None;UNX A 406 ( 4.4A);None","1.29A","5lg3G-1zd0A:undetectable","5lg3G-1zd0A:19.68"],["5LG3_H_Z80H401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","1zd0","HYPOTHETICAL PROTEIN PF0523","Pyrococcus furiosus",5,"ILE A 103;ILE A 123;VAL A  43;GLU A  98;ILE A  30","None;None;None;UNX A 406 ( 4.4A);None","1.26A","5lg3H-1zd0A:undetectable","5lg3H-1zd0A:19.68"],["6J20_A_GBQA1201_1","SUBSTANCE-P RECEPTOR,ENDOLYSIN","1zd0","HYPOTHETICAL PROTEIN PF0523","Pyrococcus furiosus",4,"ILE A 123;GLN A  29;GLU A  98;VAL A  23","None;None;UNX A 406 ( 4.4A);None","0.78A","6j20A-1zd0A:undetectable","6j20A-1zd0A:15.23"]]