SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		5 / 11 GLU A 197
ARG A 247
ASN A 134
SER A 141
LEU A 138
 None
 1.49A 1hwkB-1zd1A:
0.0		 1hwkB-1zd1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		5 / 11 GLU A 197
ARG A 247
ASN A 134
SER A 141
LEU A 138
 None
 1.47A 1hwkA-1zd1A:
0.0		 1hwkA-1zd1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		4 / 6 TYR A 172
GLY A  57
PHE A 145
SER A 141
 None
 1.39A 2a3cA-1zd1A:
undetectable		 2a3cA-1zd1A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		4 / 6 TYR A 172
GLY A  57
PHE A 145
SER A 141
 None
 1.39A 2a3cB-1zd1A:
undetectable		 2a3cB-1zd1A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		3 / 3 PHE A 265
CYH A 162
PHE A 158
 None
 1.09A 3cr5X-1zd1A:
0.0		 3cr5X-1zd1A:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		4 / 7 PHE A 158
PHE A 257
PHE A 165
TYR A 142
 None
 1.25A 3hggA-1zd1A:
undetectable		 3hggA-1zd1A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		3 / 3 VAL A  65
SER A  69
LEU A 107
 None
 0.74A 3n8xA-1zd1A:
undetectable		 3n8xA-1zd1A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		4 / 6 GLN A  70
TYR A  66
GLN A  62
SER A  69
 None
 1.31A 3peoG-1zd1A:
undetectable		 3peoG-1zd1A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		3 / 3 LYS A  13
TYR A  19
ARG A  26
 None
 1.38A 4gc9A-1zd1A:
undetectable		 4gc9A-1zd1A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		4 / 4 LEU A  96
ARG A 106
ILE A  99
ILE A 108
 None
 1.10A 5dzk2-1zd1A:
undetectable
5dzkM-1zd1A:
undetectable
5dzkN-1zd1A:
undetectable		 5dzk2-1zd1A:
0.70
5dzkM-1zd1A:
21.00
5dzkN-1zd1A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		3 / 3 CYH A 162
MET A 261
ASN A 262
 None
 1.18A 5qh8A-1zd1A:
undetectable		 5qh8A-1zd1A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1zd1 SULFOTRANSFERASE 4A1
(Homo
sapiens) 		4 / 6 VAL A 179
ASN A 134
PRO A 135
GLU A 197
 None
 1.24A 6h7uA-1zd1A:
undetectable		 6h7uA-1zd1A:
20.12