SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1zdv OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 12 LEU A  74
ALA A  45
MET A  44
LEU A  39
TYR A 127
 None
 1.21A 1kt5A-1zdvA:
undetectable		 1kt5A-1zdvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 1zdv OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		5 / 12 LEU A 111
ASN A 112
LEU A 104
LEU A  93
THR A 114
 None
 1.39A 2q7kA-1zdvA:
undetectable		 2q7kA-1zdvA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zdv OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 ILE A 115
ARG A  66
THR A  65
LEU A  64
 None
 1.02A 3wg7N-1zdvA:
undetectable
3wg7W-1zdvA:
undetectable		 3wg7N-1zdvA:
12.22
3wg7W-1zdvA:
16.67