SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zdx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 1zdx OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 8 LEU A  69
ALA A  86
LEU A  85
ILE A  37
 None
 0.93A 3cldB-1zdxA:
undetectable		 3cldB-1zdxA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 1zdx OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		3 / 3 TYR A  43
MET A  44
ILE A 115
 None
 0.77A 4c8bB-1zdxA:
undetectable		 4c8bB-1zdxA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 1zdx OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 5 GLN A 117
THR A  94
LEU A 113
LEU A  39
 None
 0.88A 4lvcB-1zdxA:
undetectable		 4lvcB-1zdxA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zdx OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 ILE A 115
ARG A  66
THR A  65
LEU A  64
 None
 1.04A 5z86N-1zdxA:
undetectable
5z86W-1zdxA:
undetectable		 5z86N-1zdxA:
12.21
5z86W-1zdxA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zdx OUTER MEMBRANE USHER
PROTEIN FIMD
(Escherichia
coli) 		4 / 6 ILE A 115
ARG A  66
THR A  65
LEU A  64
 None
 1.03A 5zcoN-1zdxA:
undetectable
5zcoW-1zdxA:
undetectable		 5zcoN-1zdxA:
12.21
5zcoW-1zdxA:
17.17