SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zea'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1ZEA_A_DHIA6_0 (MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2)	1zea	MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN (Mus musculus)	3 / 3	TRP H 47 ARG H 95 PHE H 100	None	1.30A	1zeaH-1zeaH: 33.2 1zeaL-1zeaH: 16.3	1zeaH-1zeaH: 100.00 1zeaL-1zeaH: 27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	1zea	MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN (Mus musculus)	4 / 5	TYR H 90 LEU H 80 LEU H 82 ARG H 66	None	1.16A	4em2A-1zeaH: undetectable	4em2A-1zeaH: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MF6_A_BEZA303_0 (GLUTATHIONE S-TRANSFERASE DOMAIN)	1zea	MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN (Mus musculus)	4 / 5	THR H 13 PRO H 14 PHE H 146 ASN H 84	None	1.28A	4mf6A-1zeaH: undetectable	4mf6A-1zeaH: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1zea	MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN (Mus musculus)	4 / 7	ALA H 88 THR H 87 VAL H 109 GLU H 85	None	0.75A	5ecmD-1zeaH: undetectable	5ecmD-1zeaH: 17.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZEA_A_DHIA6_0","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN;MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, L CHAIN;SHORT SYNTHETIC D-AMINO ACID PEPTIDE D2","1zea","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN","Mus musculus",3,"TRP H  47;ARG H  95;PHE H 100","None","1.30A","1zeaH-1zeaH:33.2;1zeaL-1zeaH:16.3","1zeaH-1zeaH:100.00;1zeaL-1zeaH:27.97"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","1zea","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN","Mus musculus",4,"TYR H  90;LEU H  80;LEU H  82;ARG H  66","None","1.16A","4em2A-1zeaH:undetectable","4em2A-1zeaH:18.26"],["4MF6_A_BEZA303_0","GLUTATHIONE S-TRANSFERASE DOMAIN","1zea","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN","Mus musculus",4,"THR H  13;PRO H  14;PHE H 146;ASN H  84","None","1.28A","4mf6A-1zeaH:undetectable","4mf6A-1zeaH:20.00"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1zea","MONOCLONAL ANTI-CHOLERA TOXIN IGG1 KAPPA ANTIBODY, H CHAIN","Mus musculus",4,"ALA H  88;THR H  87;VAL H 109;GLU H  85","None","0.75A","5ecmD-1zeaH:undetectable","5ecmD-1zeaH:17.67"]]