SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zes'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.86A 1v54C-1zesA:
undetectable
1v54J-1zesA:
undetectable
1v54C-1zesA:
16.80
1v54J-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.88A 1v54P-1zesA:
undetectable
1v54W-1zesA:
undetectable
1v54P-1zesA:
16.80
1v54W-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.88A 2dyrC-1zesA:
undetectable
2dyrJ-1zesA:
undetectable
2dyrC-1zesA:
16.80
2dyrJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.88A 2dyrP-1zesA:
undetectable
2dyrW-1zesA:
undetectable
2dyrP-1zesA:
16.80
2dyrW-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.91A 2eikC-1zesA:
undetectable
2eikJ-1zesA:
undetectable
2eikC-1zesA:
16.80
2eikJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.82A 2eikP-1zesA:
undetectable
2eikW-1zesA:
undetectable
2eikP-1zesA:
16.80
2eikW-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.88A 2eilC-1zesA:
undetectable
2eilJ-1zesA:
undetectable
2eilC-1zesA:
16.80
2eilJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.83A 2eilP-1zesA:
undetectable
2eilW-1zesA:
undetectable
2eilP-1zesA:
16.80
2eilW-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.84A 3ag2C-1zesA:
undetectable
3ag2C-1zesA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.80A 3ag2P-1zesA:
undetectable
3ag2W-1zesA:
undetectable
3ag2P-1zesA:
16.80
3ag2W-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.85A 3ag4C-1zesA:
undetectable
3ag4J-1zesA:
undetectable
3ag4C-1zesA:
16.80
3ag4J-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.89A 3ag4P-1zesA:
undetectable
3ag4W-1zesA:
undetectable
3ag4P-1zesA:
16.80
3ag4W-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.87A 3asnC-1zesA:
undetectable
3asnJ-1zesA:
undetectable
3asnC-1zesA:
16.80
3asnJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.88A 3asoC-1zesA:
undetectable
3asoJ-1zesA:
undetectable
3asoC-1zesA:
16.80
3asoJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 8 GLY A  98
ALA A  99
ASP A 100
THR A  83
None
None
None
BEF  A 201 (-3.5A)
0.60A 3el0A-1zesA:
undetectable
3el0A-1zesA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.77A 3x2qC-1zesA:
undetectable
3x2qJ-1zesA:
undetectable
3x2qC-1zesA:
16.80
3x2qJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.84A 3x2qP-1zesA:
undetectable
3x2qW-1zesA:
undetectable
3x2qP-1zesA:
16.80
3x2qW-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.79A 5b1aC-1zesA:
undetectable
5b1aJ-1zesA:
undetectable
5b1aC-1zesA:
16.80
5b1aJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.76A 5b1aP-1zesA:
undetectable
5b1aW-1zesA:
undetectable
5b1aP-1zesA:
16.80
5b1aW-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.93A 5b1bP-1zesA:
undetectable
5b1bW-1zesA:
undetectable
5b1bP-1zesA:
16.80
5b1bW-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.75A 5b3sC-1zesA:
undetectable
5b3sJ-1zesA:
undetectable
5b3sC-1zesA:
16.80
5b3sJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.75A 5b3sP-1zesA:
undetectable
5b3sP-1zesA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.87A 5iy5C-1zesA:
undetectable
5iy5J-1zesA:
undetectable
5iy5C-1zesA:
16.54
5iy5J-1zesA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.76A 5z84C-1zesA:
undetectable
5z84J-1zesA:
undetectable
5z84C-1zesA:
16.80
5z84J-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.76A 5z85C-1zesA:
undetectable
5z85J-1zesA:
undetectable
5z85C-1zesA:
16.80
5z85J-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.76A 5zcoC-1zesA:
undetectable
5zcoJ-1zesA:
undetectable
5zcoC-1zesA:
16.80
5zcoJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.82A 5zcqC-1zesA:
undetectable
5zcqJ-1zesA:
undetectable
5zcqC-1zesA:
16.80
5zcqJ-1zesA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
1zes PHOSPHATE REGULON
TRANSCRIPTIONAL
REGULATORY PROTEIN
PHOB

(Escherichia
coli)
4 / 7 LEU A  42
GLN A  41
PHE A  64
LEU A  68
None
0.74A 5zcqP-1zesA:
undetectable
5zcqW-1zesA:
undetectable
5zcqP-1zesA:
16.80
5zcqW-1zesA:
20.16