SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zgg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1zgg PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		3 / 3 THR A 130
LEU A 134
LEU A 141
 None
 0.65A 1mz9C-1zggA:
undetectable		 1mz9C-1zggA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1zgg PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		5 / 12 ILE A   4
LEU A  81
HIS A  87
ALA A  37
LEU A 134
 None
 1.17A 2a58A-1zggA:
2.5
2a58B-1zggA:
2.5		 2a58A-1zggA:
23.89
2a58B-1zggA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1zgg PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		5 / 12 ILE A   4
LEU A  81
HIS A  87
ALA A  37
LEU A 134
 None
 1.16A 2a58B-1zggA:
2.5
2a58C-1zggA:
2.9		 2a58B-1zggA:
23.89
2a58C-1zggA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1zgg PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		5 / 12 ILE A   4
LEU A  81
HIS A  87
ALA A  37
LEU A 134
 None
 1.16A 2a58D-1zggA:
2.9
2a58E-1zggA:
2.5		 2a58D-1zggA:
23.89
2a58E-1zggA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 1zgg PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		5 / 11 VAL A  32
ILE A   4
SER A  36
PRO A  15
SER A  14
 None
 1.30A 3bjwB-1zggA:
2.1		 3bjwB-1zggA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 1zgg PUTATIVE LOW
MOLECULAR WEIGHT
PROTEIN-TYROSINE-PHO
SPHATASE YWLE
(Bacillus
subtilis) 		4 / 8 SER A  36
ALA A  17
ALA A  51
LEU A  55
 None
 0.69A 5te8B-1zggA:
undetectable		 5te8B-1zggA:
16.18