SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 1zh1 NON-STRUCTURAL
POLYPROTEIN
(Hepacivirus
C) 		4 / 7 VAL A 121
TYR A 106
GLU A 148
PRO A 147
 None
 1.12A 3hs4A-1zh1A:
undetectable		 3hs4A-1zh1A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 1zh1 NON-STRUCTURAL
POLYPROTEIN
(Hepacivirus
C) 		3 / 3 THR A 134
THR A 135
PHE A 175
 None
 0.92A 5cxvA-1zh1A:
undetectable		 5cxvA-1zh1A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_2
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 1zh1 NON-STRUCTURAL
POLYPROTEIN
(Hepacivirus
C) 		4 / 4 ASP A 195
PRO A 192
GLU A 191
TYR A 129
 None
 1.37A 5xprA-1zh1A:
0.0		 5xprA-1zh1A:
15.70