SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_A_ZPCA1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1zhn	CD1D1 ANTIGEN (Mus musculus)	4 / 7	GLU A 105 GLU A 113 PHE A 115 VAL A 136	None	1.06A	4a97A-1zhnA: 3.5	4a97A-1zhnA: 17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_D_ZPCD1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1zhn	CD1D1 ANTIGEN (Mus musculus)	4 / 7	GLU A 105 GLU A 113 PHE A 115 VAL A 136	None	1.10A	4a97D-1zhnA: 2.3	4a97D-1zhnA: 17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M54_E_TA1E502_1 (TUBULIN BETA-2B CHAIN)	1zhn	CD1D1 ANTIGEN (Mus musculus)	5 / 12	SER A 114 GLN A 55 ARG A 173 GLY A 174 LEU A 175	FUC A 287 (-4.4A) None None None None	1.09A	5m54E-1zhnA: undetectable	5m54E-1zhnA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1zhn	CD1D1 ANTIGEN (Mus musculus)	3 / 3	TYR A 73 ARG A 74 THR A 78	PC6 A 1 (-3.9A) None None	0.97A	5z84J-1zhnA: undetectable	5z84J-1zhnA: 11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_A_ADNA502_2 (-)	1zhn	CD1D1 ANTIGEN (Mus musculus)	4 / 4	GLN A 36 THR A 37 THR A 9 LEU A 13	None	1.29A	6f3mA-1zhnA: undetectable	6f3mA-1zhnA: 17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3M_C_ADNC502_2 (-)	1zhn	CD1D1 ANTIGEN (Mus musculus)	4 / 4	GLN A 36 THR A 37 THR A 9 LEU A 13	None	1.28A	6f3mC-1zhnA: undetectable	6f3mC-1zhnA: 17.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A97_A_ZPCA1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL","1zhn","CD1D1 ANTIGEN","Mus musculus",4,"GLU A 105;GLU A 113;PHE A 115;VAL A 136","None","1.06A","4a97A-1zhnA:3.5","4a97A-1zhnA:17.87"],["4A97_D_ZPCD1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","1zhn","CD1D1 ANTIGEN","Mus musculus",4,"GLU A 105;GLU A 113;PHE A 115;VAL A 136","None","1.10A","4a97D-1zhnA:2.3","4a97D-1zhnA:17.87"],["5M54_E_TA1E502_1","TUBULIN BETA-2B CHAIN","1zhn","CD1D1 ANTIGEN","Mus musculus",5,"SER A 114;GLN A  55;ARG A 173;GLY A 174;LEU A 175","FUC A 287 (-4.4A);None;None;None;None","1.09A","5m54E-1zhnA:undetectable","5m54E-1zhnA:19.53"],["5Z84_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1zhn","CD1D1 ANTIGEN","Mus musculus",3,"TYR A  73;ARG A  74;THR A  78","PC6 A   1 (-3.9A);None;None","0.97A","5z84J-1zhnA:undetectable","5z84J-1zhnA:11.83"],["6F3M_A_ADNA502_2","-","1zhn","CD1D1 ANTIGEN","Mus musculus",4,"GLN A  36;THR A  37;THR A   9;LEU A  13","None","1.29A","6f3mA-1zhnA:undetectable","6f3mA-1zhnA:17.81"],["6F3M_C_ADNC502_2","-","1zhn","CD1D1 ANTIGEN","Mus musculus",4,"GLN A  36;THR A  37;THR A   9;LEU A  13","None","1.28A","6f3mC-1zhnA:undetectable","6f3mC-1zhnA:17.63"]]