SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ziq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 1ziq GAMMA CRYSTALLIN E
(Rattus
norvegicus) 		3 / 3 PHE A1005
LEU A1044
LEU A1057
 None
 0.51A 1mx1E-1ziqA:
undetectable		 1mx1E-1ziqA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1ziq GAMMA CRYSTALLIN E
(Rattus
norvegicus) 		5 / 12 ARG A1139
GLY A1164
ILE A1091
ARG A1167
LEU A1166
 None
 1.19A 3iv6C-1ziqA:
undetectable		 3iv6C-1ziqA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ziq GAMMA CRYSTALLIN E
(Rattus
norvegicus) 		4 / 8 ILE A1089
LEU A1145
VAL A1163
GLY A1164
 None
 0.82A 3w1wA-1ziqA:
undetectable		 3w1wA-1ziqA:
18.71