SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zjj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		4 / 4 ILE A 183
MET A  77
VAL A 119
GLY A 150
 None
 1.32A 1e06B-1zjjA:
undetectable		 1e06B-1zjjA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		5 / 9 VAL A 253
ILE A  26
LEU A  29
PHE A   6
THR A 231
 None
 1.35A 3fl9H-1zjjA:
undetectable		 3fl9H-1zjjA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		3 / 3 ARG A 211
ASP A 238
ASP A 213
 None
 0.90A 3jb3A-1zjjA:
undetectable		 3jb3A-1zjjA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		4 / 8 SER A 234
ASP A 215
LEU A 157
PRO A 158
 None
MG  A1001 ( 4.6A)
None
None
 1.16A 3jq7B-1zjjA:
undetectable		 3jq7B-1zjjA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		5 / 12 GLY A 209
THR A 214
ILE A 227
ASP A   7
VAL A  11
 None
None
None
MG  A1001 (-2.6A)
None
 1.05A 3nvkI-1zjjA:
undetectable		 3nvkI-1zjjA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		5 / 12 VAL A 229
LEU A 248
PHE A   6
LEU A 260
VAL A   2
 None
 1.17A 3w68A-1zjjA:
2.1		 3w68A-1zjjA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		5 / 12 VAL A 229
LEU A 248
PHE A   6
LEU A 260
VAL A   2
 None
 1.07A 3w68B-1zjjA:
undetectable		 3w68B-1zjjA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		4 / 6 ARG A 112
ASP A 129
GLU A  92
LEU A 108
 None
 1.26A 4ax8A-1zjjA:
2.5		 4ax8A-1zjjA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		4 / 6 ILE A  34
PRO A  35
PHE A  36
PHE A   6
 None
 0.89A 4fgkA-1zjjA:
undetectable		 4fgkA-1zjjA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		3 / 3 SER A 169
ALA A 173
VAL A 176
 None
 0.65A 4x20C-1zjjA:
undetectable		 4x20C-1zjjA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		4 / 6 ALA A 146
THR A 147
VAL A 122
VAL A 180
 None
 1.05A 5eckD-1zjjA:
1.2		 5eckD-1zjjA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		5 / 12 GLY A 125
GLY A 166
ARG A 211
GLY A  70
SER A  69
 None
 1.23A 5hikA-1zjjA:
2.9		 5hikA-1zjjA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		3 / 3 VAL A 229
LYS A 225
MET A 224
 None
 1.05A 5nknA-1zjjA:
undetectable		 5nknA-1zjjA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		5 / 12 SER A 169
GLY A 166
GLY A 125
VAL A 124
THR A 151
 None
 1.34A 5o4yD-1zjjA:
undetectable
5o4yE-1zjjA:
undetectable		 5o4yD-1zjjA:
9.91
5o4yE-1zjjA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		3 / 3 VAL A 123
VAL A  88
GLN A  99
 None
 0.71A 5qglA-1zjjA:
undetectable		 5qglA-1zjjA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1zjj HYPOTHETICAL PROTEIN
PH1952
(Pyrococcus
horikoshii) 		3 / 3 VAL A 123
VAL A  88
GLN A  99
 None
 0.71A 5qhgA-1zjjA:
undetectable		 5qhgA-1zjjA:
20.82