SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 11 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.13A 1akdA-1zjrA:
undetectable		 1akdA-1zjrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 11 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.16A 1phgA-1zjrA:
undetectable		 1phgA-1zjrA:
19.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 12 GLY A 126
GLY A 131
ILE A 163
LEU A 155
VAL A 157
ALA A 160
 GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
None
GOL  A 529 (-3.7A)
GOL  A 529 (-3.6A)
 1.15A 1v2xA-1zjrA:
26.8		 1v2xA-1zjrA:
47.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 GLY A 126
GLY A 131
MET A 148
SER A 154
LEU A 155
VAL A 157
ALA A 160
 GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
GOL  A 529 (-3.6A)
 0.69A 1v2xA-1zjrA:
26.8		 1v2xA-1zjrA:
47.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
VAL A 157
ALA A 160
 GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
GOL  A 529 (-3.6A)
 0.43A 1v2xA-1zjrA:
26.8		 1v2xA-1zjrA:
47.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 LEU A 105
GLY A 126
GLY A 131
MET A 148
SER A 154
LEU A 155
VAL A 157
 GOL  A 530 ( 4.5A)
GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 1.09A 1v2xA-1zjrA:
26.8		 1v2xA-1zjrA:
47.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 LEU A 105
GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
VAL A 157
 GOL  A 530 ( 4.5A)
GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 0.80A 1v2xA-1zjrA:
26.8		 1v2xA-1zjrA:
47.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		3 / 3 GLU A 173
GLU A 167
LEU A  26
 None
 0.72A 1v8bA-1zjrA:
2.7		 1v8bA-1zjrA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		3 / 3 GLU A 173
GLU A 167
LEU A  26
 None
 0.76A 1v8bB-1zjrA:
2.7		 1v8bB-1zjrA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 11 GLY A 126
GLY A 131
MET A 148
LEU A 155
ALA A 160
 GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
None
GOL  A 529 (-3.6A)
 0.96A 1x7pA-1zjrA:
17.5
1x7pB-1zjrA:
17.5		 1x7pA-1zjrA:
21.70
1x7pB-1zjrA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 11 THR A 103
GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
ALA A 160
 GOL  A 529 (-3.0A)
GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.6A)
 0.91A 1x7pA-1zjrA:
17.5
1x7pB-1zjrA:
17.5		 1x7pA-1zjrA:
21.70
1x7pB-1zjrA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 10 THR A 103
GLY A 126
ILE A 146
MET A 148
LEU A 155
ALA A 160
 GOL  A 529 (-3.0A)
GOL  A 529 (-4.0A)
None
None
None
GOL  A 529 (-3.6A)
 0.60A 1x7pA-1zjrA:
17.5
1x7pB-1zjrA:
17.6		 1x7pA-1zjrA:
21.70
1x7pB-1zjrA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 11 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.12A 2a1nA-1zjrA:
undetectable		 2a1nA-1zjrA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 12 TYR A 117
PHE A 112
VAL A 110
ALA A 140
VAL A 115
 None
 1.45A 2g70B-1zjrA:
undetectable		 2g70B-1zjrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 12 TYR A 117
PHE A 112
VAL A 110
ALA A 140
VAL A 115
 None
 1.42A 2g72A-1zjrA:
undetectable		 2g72A-1zjrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 11 VAL A 132
GLY A 126
ILE A 164
LEU A 123
THR A 161
 None
GOL  A 529 (-4.0A)
None
None
None
 1.42A 3bf1C-1zjrA:
undetectable
3bf1D-1zjrA:
undetectable		 3bf1C-1zjrA:
25.66
3bf1D-1zjrA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 11 GLY A 126
GLY A 131
ILE A 163
LEU A 155
VAL A 157
ALA A 160
 GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
None
GOL  A 529 (-3.7A)
GOL  A 529 (-3.6A)
 1.20A 3dcmX-1zjrA:
12.5		 3dcmX-1zjrA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 11 THR A 103
GLY A 126
ILE A 146
LEU A 155
VAL A 157
ALA A 160
 GOL  A 529 (-3.0A)
GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.7A)
GOL  A 529 (-3.6A)
 0.59A 3dcmX-1zjrA:
12.5		 3dcmX-1zjrA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 12 GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
 GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
 0.74A 3gyqA-1zjrA:
16.4
3gyqB-1zjrA:
16.9		 3gyqA-1zjrA:
23.67
3gyqB-1zjrA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 11 GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
VAL A 157
 GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 0.67A 3gyqB-1zjrA:
16.9		 3gyqB-1zjrA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 10 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.15A 3lxiA-1zjrA:
undetectable		 3lxiA-1zjrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 11 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.14A 3lxiB-1zjrA:
undetectable		 3lxiB-1zjrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 12 ASN A  38
GLY A 126
GLY A 131
MET A 148
ASN A 156
VAL A 157
 None
GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
None
GOL  A 529 (-3.7A)
 0.90A 3nk7A-1zjrA:
17.2		 3nk7A-1zjrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 ASN A  38
GLY A 126
ILE A 146
MET A 148
SER A 154
ASN A 156
VAL A 157
 None
GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 0.65A 3nk7A-1zjrA:
17.2		 3nk7A-1zjrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 12 GLY A 126
GLY A 131
ILE A 163
ASN A 156
VAL A 157
 GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
None
GOL  A 529 (-3.7A)
 1.02A 3nk7A-1zjrA:
17.2		 3nk7A-1zjrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 12 LEU A 155
THR A 161
GLY A 131
ILE A 163
VAL A 145
 None
None
GOL  A 530 (-3.7A)
None
None
 1.05A 3nk7A-1zjrA:
17.2		 3nk7A-1zjrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 ASN A  38
GLY A 126
GLY A 131
MET A 148
SER A 154
LEU A 155
VAL A 157
 None
GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 0.79A 3nk7B-1zjrA:
17.4		 3nk7B-1zjrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 ASN A  38
GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
VAL A 157
 None
GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 0.63A 3nk7B-1zjrA:
17.4		 3nk7B-1zjrA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 9 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.11A 4c9kB-1zjrA:
undetectable		 4c9kB-1zjrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 9 GLY A 126
ILE A 146
MET A 148
SER A 154
VAL A 157
 GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
GOL  A 529 (-3.7A)
 0.63A 4x3mA-1zjrA:
15.4		 4x3mA-1zjrA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 9 GLY A 126
ILE A 146
MET A 148
SER A 154
LEU A 155
VAL A 157
 GOL  A 529 (-4.0A)
None
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.7A)
 0.61A 4x3mB-1zjrA:
15.4		 4x3mB-1zjrA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 12 ILE A  80
VAL A  28
ASP A  31
ASN A  32
ILE A  42
 None
 1.11A 4xe0A-1zjrA:
undetectable		 4xe0A-1zjrA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 9 TYR A 117
GLY A 162
THR A  45
VAL A  51
VAL A  49
 None
 1.13A 5cp4A-1zjrA:
undetectable		 5cp4A-1zjrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		6 / 12 LEU A 105
GLY A 126
GLY A 131
SER A 154
LEU A 155
ALA A 160
 GOL  A 530 ( 4.5A)
GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.6A)
 1.19A 5l0zA-1zjrA:
9.6		 5l0zA-1zjrA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 12 THR A 103
LEU A 105
GLY A 126
ILE A 146
SER A 154
LEU A 155
ALA A 160
 GOL  A 529 (-3.0A)
GOL  A 530 ( 4.5A)
GOL  A 529 (-4.0A)
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.6A)
 0.87A 5l0zA-1zjrA:
9.6		 5l0zA-1zjrA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		5 / 10 GLY A 126
GLY A 131
SER A 154
LEU A 155
ALA A 160
 GOL  A 529 (-4.0A)
GOL  A 530 (-3.7A)
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.6A)
 1.04A 5l0zB-1zjrA:
17.8		 5l0zB-1zjrA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		7 / 10 THR A 103
LEU A 105
GLY A 126
ILE A 146
SER A 154
LEU A 155
ALA A 160
 GOL  A 529 (-3.0A)
GOL  A 530 ( 4.5A)
GOL  A 529 (-4.0A)
None
GOL  A 529 (-3.5A)
None
GOL  A 529 (-3.6A)
 0.82A 5l0zB-1zjrA:
17.8		 5l0zB-1zjrA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 1zjr TRNA
(GUANOSINE-2'-O-)-ME
THYLTRANSFERASE
(Aquifex
aeolicus) 		4 / 7 ILE A 191
TRP A  77
TRP A 195
ASP A 199
 None
 1.09A 5nr3A-1zjrA:
0.0		 5nr3A-1zjrA:
19.81