SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 7 GLY A  29
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
CA  A1001 ( 2.3A)
None
None
None
 0.96A 1th6A-1zl7A:
19.6		 1th6A-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
CA  A1001 ( 2.3A)
None
None
None
 0.61A 1th6A-1zl7A:
19.6		 1th6A-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 12 GLY A  29
GLY A  32
TYR A  51
PRO A  59
LYS A  60
 None
CA  A1001 (-3.4A)
None
None
None
 1.13A 1y4lA-1zl7A:
20.3		 1y4lA-1zl7A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 12 LEU A   2
GLY A  29
GLY A  32
PRO A  59
LYS A  60
 None
None
CA  A1001 (-3.4A)
None
None
 1.14A 1y4lA-1zl7A:
20.3		 1y4lA-1zl7A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 7 GLY A  29
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
CA  A1001 ( 2.3A)
None
None
None
 0.96A 2armA-1zl7A:
19.6		 2armA-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 7 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
CA  A1001 ( 2.3A)
None
None
None
 0.61A 2armA-1zl7A:
19.6		 2armA-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		4 / 6 LEU A   2
HIS A  47
ASP A  48
TYR A  51
 None
None
CA  A1001 ( 2.3A)
None
 0.80A 2dpzA-1zl7A:
19.2		 2dpzA-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		3 / 3 ASP A  48
TYR A  51
LYS A  60
 CA  A1001 ( 2.3A)
None
None
 0.64A 2othA-1zl7A:
19.2		 2othA-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
CA  A1001 ( 2.3A)
None
None
 0.51A 3fo7A-1zl7A:
19.7		 3fo7A-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
CA  A1001 ( 2.3A)
None
None
 0.44A 3h1xA-1zl7A:
19.7		 3h1xA-1zl7A:
53.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		4 / 5 PHE A   5
ILE A   9
GLY A  29
HIS A  47
 None
 0.62A 3r0lD-1zl7A:
21.2		 3r0lD-1zl7A:
54.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 9 VAL A  46
ALA A  92
PHE A  96
TYR A 103
TYR A  24
 None
 1.49A 4lb2B-1zl7A:
undetectable		 4lb2B-1zl7A:
13.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 12 GLY A  29
GLY A  31
TYR A  51
ASN A  58
PRO A  59
 None
CA  A1001 (-3.9A)
None
None
None
 0.81A 6ce2B-1zl7A:
18.5		 6ce2B-1zl7A:
51.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2
(Bothrops
jararacussu) 		5 / 12 GLY A  29
GLY A  31
TYR A  51
PRO A  59
LYS A  60
 None
CA  A1001 (-3.9A)
None
None
None
 1.12A 6ce2B-1zl7A:
18.5		 6ce2B-1zl7A:
51.64