SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_1
(TRANSTHYRETIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 LEU A 108
LEU A  49
SER A  34
SER A  36
 None
 0.64A 1dvxA-1zliA:
undetectable		 1dvxA-1zliA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.92A 1nsiA-1zliA:
undetectable
1nsiB-1zliA:
undetectable		 1nsiA-1zliA:
21.57
1nsiB-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.95A 1nsiA-1zliA:
undetectable
1nsiB-1zliA:
undetectable		 1nsiA-1zliA:
21.57
1nsiB-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.92A 1nsiC-1zliA:
undetectable
1nsiD-1zliA:
undetectable		 1nsiC-1zliA:
21.57
1nsiD-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.94A 1nsiC-1zliA:
undetectable
1nsiD-1zliA:
undetectable		 1nsiC-1zliA:
21.57
1nsiD-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		3 / 3 ASP A 255
HIS A 196
ASP A  65
 None
ZN  A 501 (-3.3A)
None
 0.72A 1nw5A-1zliA:
undetectable		 1nw5A-1zliA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ARG A 145
HIS A 196
TYR A 248
ILE A 203
 None
ZN  A 501 (-3.3A)
None
None
 1.41A 1tdnA-1zliA:
undetectable		 1tdnA-1zliA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		3 / 3 LEU A 108
LEU A  49
SER A  36
 None
 0.68A 1tlmA-1zliA:
undetectable		 1tlmA-1zliA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 4 LYS A 190
LEU A 308
LEU A 305
SER A 302
 None
 1.37A 1tt6A-1zliA:
0.0		 1tt6A-1zliA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 12 TYR A 192
LEU A 108
PHE A 147
SER A 172
ILE A  47
 None
 1.38A 1xosA-1zliA:
undetectable		 1xosA-1zliA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
ZN  A 501 ( 4.8A)
 1.30A 2c8aA-1zliA:
undetectable		 2c8aA-1zliA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 7 GLY A 278
SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
None
ZN  A 501 ( 4.8A)
 1.33A 2c8aB-1zliA:
undetectable		 2c8aB-1zliA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 SER A 199
SER A 197
PHE A 279
GLU A 270
 None
None
None
ZN  A 501 ( 4.8A)
 1.34A 2c8aC-1zliA:
undetectable		 2c8aC-1zliA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 5 SER A 197
LEU A 280
GLY A 278
ARG A 124
 None
 0.96A 2j2pA-1zliA:
undetectable
2j2pB-1zliA:
undetectable		 2j2pA-1zliA:
23.00
2j2pB-1zliA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 ARG A 124
SER A 197
LEU A 280
GLY A 278
 None
 1.03A 2j2pA-1zliA:
undetectable
2j2pC-1zliA:
undetectable		 2j2pA-1zliA:
23.00
2j2pC-1zliA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 ARG A 124
SER A 197
LEU A 280
GLY A 278
 None
 1.01A 2j2pD-1zliA:
undetectable
2j2pF-1zliA:
undetectable		 2j2pD-1zliA:
23.00
2j2pF-1zliA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.93A 2nsiA-1zliA:
undetectable
2nsiB-1zliA:
undetectable		 2nsiA-1zliA:
21.57
2nsiB-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.93A 2nsiA-1zliA:
undetectable
2nsiB-1zliA:
undetectable		 2nsiA-1zliA:
21.57
2nsiB-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.94A 2nsiC-1zliA:
undetectable
2nsiD-1zliA:
undetectable		 2nsiC-1zliA:
21.57
2nsiD-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.95A 2nsiC-1zliA:
undetectable
2nsiD-1zliA:
undetectable		 2nsiC-1zliA:
21.57
2nsiD-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ILE A 183
ARG A 184
PHE A 147
GLU A 171
 None
 1.07A 2qebA-1zliA:
undetectable		 2qebA-1zliA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ILE A 183
ARG A 184
PHE A 147
GLU A 171
 None
 1.02A 2qebB-1zliA:
undetectable		 2qebB-1zliA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 12 LEU A 193
ILE A 195
ALA A 191
VAL A 304
PHE A  78
 None
 1.30A 2qo4A-1zliA:
undetectable		 2qo4A-1zliA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		3 / 3 GLU A 270
HIS A  69
GLU A  72
 ZN  A 501 ( 4.8A)
ZN  A 501 (-3.1A)
ZN  A 501 (-2.1A)
 0.78A 2x45B-1zliA:
undetectable		 2x45B-1zliA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		3 / 3 GLU A 270
HIS A  69
GLU A  72
 ZN  A 501 ( 4.8A)
ZN  A 501 (-3.1A)
ZN  A 501 (-2.1A)
 0.80A 2x45C-1zliA:
undetectable		 2x45C-1zliA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 11 THR A 268
TYR A 248
GLY A 253
SER A 254
ARG A 127
 None
None
None
None
ZN  A 501 ( 4.4A)
 1.11A 2xf3A-1zliA:
0.0		 2xf3A-1zliA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 11 THR A 268
TYR A 248
GLY A 253
SER A 254
ARG A 127
 None
None
None
None
ZN  A 501 ( 4.4A)
 1.11A 2xf3B-1zliA:
0.0		 2xf3B-1zliA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 11 THR A 268
TYR A 248
GLY A 253
SER A 254
ARG A 127
 None
None
None
None
ZN  A 501 ( 4.4A)
 1.10A 2xfsB-1zliA:
0.0		 2xfsB-1zliA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 8 GLY A 253
GLY A 252
ILE A 154
SER A 207
 None
 0.65A 3d41A-1zliA:
2.8		 3d41A-1zliA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.89A 3e7gA-1zliA:
undetectable
3e7gB-1zliA:
undetectable		 3e7gA-1zliA:
21.72
3e7gB-1zliA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.92A 3e7gA-1zliA:
undetectable
3e7gB-1zliA:
undetectable		 3e7gA-1zliA:
21.72
3e7gB-1zliA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.94A 3e7gC-1zliA:
undetectable
3e7gD-1zliA:
undetectable		 3e7gC-1zliA:
21.72
3e7gD-1zliA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 8 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.93A 3e7gC-1zliA:
undetectable
3e7gD-1zliA:
undetectable		 3e7gC-1zliA:
21.72
3e7gD-1zliA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 THR A 129
GLY A 115
ASN A 112
GLY A  44
 None
 0.86A 3tajA-1zliA:
undetectable		 3tajA-1zliA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 8 ILE A 297
ILE A  62
PHE A 105
GLU A 306
LEU A 222
 None
 1.42A 3ua5A-1zliA:
undetectable		 3ua5A-1zliA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 8 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.94A 4cx7A-1zliA:
undetectable
4cx7B-1zliA:
undetectable		 4cx7A-1zliA:
21.57
4cx7B-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 8 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.96A 4cx7A-1zliA:
undetectable
4cx7B-1zliA:
undetectable		 4cx7A-1zliA:
21.57
4cx7B-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 8 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.98A 4cx7C-1zliA:
undetectable
4cx7D-1zliA:
undetectable		 4cx7C-1zliA:
21.57
4cx7D-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.94A 4cx7C-1zliA:
undetectable
4cx7D-1zliA:
undetectable		 4cx7C-1zliA:
21.57
4cx7D-1zliA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 12 VAL A 300
ALA A 296
PHE A 267
SER A 266
LEU A 219
 None
 1.19A 4eckA-1zliA:
undetectable		 4eckA-1zliA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 THR A 129
GLY A 115
ASN A 112
GLY A  44
 None
 0.81A 4fjpA-1zliA:
undetectable		 4fjpA-1zliA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 THR A 129
GLY A 115
ASN A 112
GLY A  44
 None
 0.86A 4forA-1zliA:
undetectable		 4forA-1zliA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		3 / 3 TYR A 208
GLN A 261
TRP A 151
 None
 0.95A 4kn2C-1zliA:
undetectable		 4kn2C-1zliA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.96A 4nosA-1zliA:
undetectable
4nosB-1zliA:
undetectable		 4nosA-1zliA:
21.15
4nosB-1zliA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 7 ARG A  35
ILE A  18
TRP A  15
GLU A  16
 None
 0.98A 4nosC-1zliA:
undetectable
4nosD-1zliA:
undetectable		 4nosC-1zliA:
21.15
4nosD-1zliA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		4 / 6 TRP A  15
GLU A  16
ARG A  35
ILE A  18
 None
 0.94A 4nosC-1zliA:
undetectable
4nosD-1zliA:
undetectable		 4nosC-1zliA:
21.15
4nosD-1zliA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		3 / 3 GLU A 175
ILE A 139
ALA A  70
 None
 0.62A 4wnwB-1zliA:
undetectable		 4wnwB-1zliA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 12 PHE A  78
ILE A 195
LEU A 271
ALA A 296
LEU A 230
 None
 1.03A 5zwrA-1zliA:
undetectable		 5zwrA-1zliA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1zli CARBOXYPEPTIDASE B
(Homo
sapiens) 		5 / 12 PHE A  78
ILE A 195
LEU A 271
ALA A 296
LEU A 230
 None
 1.00A 5zwrB-1zliA:
undetectable		 5zwrB-1zliA:
21.20