SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zlj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 1zlj DORMANCY SURVIVAL
REGULATOR
(Mycobacterium
tuberculosis) 		5 / 9 ASN A 167
LEU A 161
ALA A 200
LEU A 158
LEU A 192
 None
 1.37A 1hwiA-1zljA:
undetectable		 1hwiA-1zljA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 1zlj DORMANCY SURVIVAL
REGULATOR
(Mycobacterium
tuberculosis) 		5 / 10 ARG A 197
ALA A 201
ALA A 200
LEU A 188
LEU A 158
 None
 1.04A 2bxgB-1zljA:
undetectable		 2bxgB-1zljA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AY4_A_TPFA506_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 1zlj DORMANCY SURVIVAL
REGULATOR
(Mycobacterium
tuberculosis) 		5 / 10 MET A 194
ALA A 201
PHE A 203
ALA A 204
LEU A 150
 None
 1.40A 6ay4A-1zljA:
undetectable		 6ay4A-1zljA:
11.32