SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 ILE A 154
ILE A 153
LEU A 115
LEU A 111
ILE A  76
 None
 1.02A 1bsxA-1zmbA:
undetectable		 1bsxA-1zmbA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 ILE A 154
ILE A 153
LEU A 115
LEU A 111
ILE A  76
 None
 1.02A 1bsxB-1zmbA:
undetectable		 1bsxB-1zmbA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 ILE A  72
ILE A  73
GLU A 253
TYR A 256
ILE A 257
 None
 1.23A 1jtxA-1zmbA:
undetectable		 1jtxA-1zmbA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_C_BEZC5013_0
(CES1 PROTEIN)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 8 GLY A  81
GLY A  82
SER A  11
ILE A 206
HIS A 207
 None
 0.97A 1yajC-1zmbA:
3.4		 1yajC-1zmbA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 4 GLY A  82
SER A  11
ILE A 206
HIS A 207
 None
 0.98A 1yajJ-1zmbA:
3.8		 1yajJ-1zmbA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 GLY A 159
GLU A 120
PHE A 216
HIS A 117
 None
 1.12A 2ackA-1zmbA:
4.2		 2ackA-1zmbA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 6 PHE A 224
ARG A 227
GLY A 113
THR A 112
 None
 1.10A 2f7fA-1zmbA:
2.5		 2f7fA-1zmbA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 PRO A  50
SER A  52
GLU A  80
ARG A  16
 None
 1.04A 2v2gA-1zmbA:
undetectable
2v2gB-1zmbA:
undetectable		 2v2gA-1zmbA:
21.97
2v2gB-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 PRO A  50
VAL A  51
SER A  52
ARG A  16
 None
 0.87A 2v2gA-1zmbA:
undetectable
2v2gB-1zmbA:
undetectable		 2v2gA-1zmbA:
21.97
2v2gB-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 7 PRO A  50
VAL A  51
SER A  52
GLU A  80
ARG A  16
 None
 1.07A 2v2gA-1zmbA:
undetectable
2v2gB-1zmbA:
undetectable		 2v2gA-1zmbA:
21.97
2v2gB-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 PRO A  50
SER A  52
GLU A  80
ARG A  16
 None
 1.03A 2v2gC-1zmbA:
undetectable
2v2gD-1zmbA:
undetectable		 2v2gC-1zmbA:
21.97
2v2gD-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 PRO A  50
VAL A  51
SER A  52
ARG A  16
 None
 0.88A 2v2gC-1zmbA:
undetectable
2v2gD-1zmbA:
undetectable		 2v2gC-1zmbA:
21.97
2v2gD-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 7 PRO A  50
VAL A  51
SER A  52
GLU A  80
ARG A  16
 None
 1.07A 2v2gC-1zmbA:
undetectable
2v2gD-1zmbA:
undetectable		 2v2gC-1zmbA:
21.97
2v2gD-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 PRO A  50
VAL A  51
SER A  52
ARG A  16
 None
 0.89A 2v32A-1zmbA:
undetectable
2v32B-1zmbA:
undetectable		 2v32A-1zmbA:
21.97
2v32B-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 8 PRO A  50
VAL A  51
SER A  52
GLU A  80
ARG A  16
 None
 1.11A 2v32A-1zmbA:
undetectable
2v32B-1zmbA:
undetectable		 2v32A-1zmbA:
21.97
2v32B-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 PRO A  50
VAL A  51
SER A  52
ARG A  16
 None
 0.87A 2v32C-1zmbA:
undetectable
2v32D-1zmbA:
undetectable		 2v32C-1zmbA:
21.97
2v32D-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 PRO A  50
VAL A  51
SER A  52
ARG A  16
 None
 0.86A 2v32C-1zmbA:
undetectable
2v32D-1zmbA:
undetectable		 2v32C-1zmbA:
21.97
2v32D-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 9 PRO A  50
VAL A  51
SER A  52
GLU A  80
ARG A  16
 None
 1.10A 2v41A-1zmbA:
undetectable
2v41B-1zmbA:
undetectable		 2v41A-1zmbA:
21.97
2v41B-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 9 PRO A  50
VAL A  51
SER A  52
GLU A  80
ARG A  16
 None
 1.06A 2v41A-1zmbA:
undetectable
2v41B-1zmbA:
undetectable		 2v41A-1zmbA:
21.97
2v41B-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 PRO A  50
VAL A  51
SER A  52
GLU A  80
 None
 0.93A 2v41C-1zmbA:
undetectable
2v41D-1zmbA:
undetectable		 2v41C-1zmbA:
21.97
2v41D-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 PRO A  50
VAL A  51
SER A  52
GLU A  80
 None
 1.02A 2v41C-1zmbA:
undetectable
2v41D-1zmbA:
undetectable		 2v41C-1zmbA:
21.97
2v41D-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 7 PRO A  50
VAL A  51
SER A  52
GLU A  80
ARG A  16
 None
 1.06A 2v41E-1zmbA:
undetectable
2v41F-1zmbA:
undetectable		 2v41E-1zmbA:
21.97
2v41F-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 PRO A  50
VAL A  51
SER A  52
GLU A  80
 None
 1.00A 2v41G-1zmbA:
undetectable
2v41H-1zmbA:
undetectable		 2v41G-1zmbA:
21.97
2v41H-1zmbA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 GLY A  17
GLY A  15
ILE A  19
ASN A  20
PHE A 216
 None
 1.19A 2vdvE-1zmbA:
3.2		 2vdvE-1zmbA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 11 GLY A  17
GLY A  15
ILE A  19
ASN A  20
PHE A 216
 None
 1.19A 2vdvF-1zmbA:
3.2		 2vdvF-1zmbA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		3 / 3 SER A 212
GLN A 213
PHE A 216
 None
 0.67A 3g4lC-1zmbA:
undetectable		 3g4lC-1zmbA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 GLU A  43
GLY A  58
PHE A 221
ILE A  30
ASN A 244
 None
 1.33A 3ps9A-1zmbA:
2.8		 3ps9A-1zmbA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 ARG A  16
ALA A  14
MET A   7
ALA A  79
 None
 1.45A 3tx2A-1zmbA:
1.3		 3tx2A-1zmbA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 6 ILE A 114
ILE A  72
TRP A  38
TRP A  64
 None
 1.42A 3weoA-1zmbA:
undetectable		 3weoA-1zmbA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 11 LEU A 158
SER A 197
ASN A 178
PHE A 193
PHE A 216
 None
 1.44A 4evrA-1zmbA:
0.4		 4evrA-1zmbA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 ILE A 206
GLY A 119
ASP A  86
ILE A  85
SER A 123
 None
 1.00A 4iv0B-1zmbA:
2.6		 4iv0B-1zmbA:
26.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 LEU A 142
GLY A 113
ASN A 190
GLU A 110
LEU A 111
 None
 1.21A 4x61A-1zmbA:
2.2		 4x61A-1zmbA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 7 PHE A  95
ILE A 138
GLY A   9
TYR A 220
 None
 0.92A 5h3aA-1zmbA:
undetectable		 5h3aA-1zmbA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 11 ILE A  85
TRP A  88
TYR A 131
ILE A 177
ILE A 154
 None
 1.14A 5hw8A-1zmbA:
undetectable
5hw8D-1zmbA:
undetectable		 5hw8A-1zmbA:
18.59
5hw8D-1zmbA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 GLY A 157
GLY A 159
ASN A  12
ILE A 155
LEU A 181
 None
 0.95A 6b3aA-1zmbA:
4.0		 6b3aA-1zmbA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		5 / 12 GLY A 157
GLY A 159
ASN A  12
ILE A 155
LEU A 181
 None
 0.93A 6b3bA-1zmbA:
2.9		 6b3bA-1zmbA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		4 / 8 GLY A 156
LEU A 181
GLN A 182
LEU A 135
 None
 0.75A 6czmD-1zmbA:
undetectable
6czmF-1zmbA:
undetectable		 6czmD-1zmbA:
20.85
6czmF-1zmbA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 1zmb ACETYLXYLAN ESTERASE
RELATED ENZYME
(Clostridium
acetobutylicum) 		3 / 3 TRP A  38
GLU A 107
GLU A 101
 None
 1.00A 6fhwA-1zmbA:
undetectable		 6fhwA-1zmbA:
16.87