SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zmf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)
1zmf PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
E

(Homo
sapiens)
4 / 6 THR A 255
SER A 235
LEU A 233
THR A 251
None
0.88A 3deuB-1zmfA:
undetectable
3deuB-1zmfA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)
1zmf PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
E

(Homo
sapiens)
4 / 8 GLY A 211
CYH A 297
GLY A 200
PHE A 189
None
0.99A 3ko0O-1zmfA:
undetectable
3ko0Q-1zmfA:
undetectable
3ko0O-1zmfA:
19.21
3ko0Q-1zmfA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)
1zmf PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
E

(Homo
sapiens)
5 / 12 GLY A 245
ILE A 214
ASN A 238
PHE A 172
LEU A 234
None
0.99A 5fa8A-1zmfA:
undetectable
5fa8A-1zmfA:
21.51