SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ALA A 187
LEU A 367
PHE A 366
LEU A 174
LEU A 178
 None
 1.15A 1dtlA-1zmrA:
undetectable		 1dtlA-1zmrA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 5 LEU A  11
VAL A  16
CYH A 133
ALA A 130
 None
 0.86A 1mz9D-1zmrA:
undetectable		 1mz9D-1zmrA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 4 LEU A  81
SER A  40
LEU A  48
LEU A 106
 None
 1.18A 1yajA-1zmrA:
1.3		 1yajA-1zmrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 SER A 126
TYR A 129
ILE A 154
VAL A 112
LEU A 125
 None
 1.25A 1z9hA-1zmrA:
undetectable		 1z9hA-1zmrA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 SER A 126
TYR A 129
ILE A 154
VAL A 112
LEU A 125
 None
 1.26A 1z9hB-1zmrA:
undetectable		 1z9hB-1zmrA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 SER A 126
TYR A 129
ILE A 154
VAL A 112
LEU A 125
 None
 1.25A 1z9hC-1zmrA:
undetectable		 1z9hC-1zmrA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A  18
VAL A  56
LEU A 106
VAL A 108
LEU A  81
 None
 0.94A 2aw1A-1zmrA:
undetectable		 2aw1A-1zmrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 9 ILE A 188
GLY A 190
PRO A 254
VAL A 253
ILE A 251
 None
 1.13A 2r5qA-1zmrA:
undetectable		 2r5qA-1zmrA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 9 ILE A 188
GLY A 190
PRO A 254
VAL A 253
ILE A 251
 None
 1.13A 2r5qC-1zmrA:
undetectable		 2r5qC-1zmrA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 9 ASP A 342
VAL A 312
GLY A 216
ILE A 217
THR A 322
 None
 1.15A 3el4B-1zmrA:
undetectable		 3el4B-1zmrA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 8 LEU A 198
GLY A 216
ALA A 218
ILE A 251
 None
 0.76A 3jusA-1zmrA:
undetectable		 3jusA-1zmrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 8 LEU A 198
GLY A 216
ALA A 218
ILE A 251
 None
 0.76A 3jusA-1zmrA:
undetectable		 3jusA-1zmrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 GLU A 170
GLY A 142
VAL A 200
GLY A 339
ARG A  36
 None
 1.04A 3k13A-1zmrA:
undetectable		 3k13A-1zmrA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 7 GLY A 340
GLY A 190
PHE A 369
PHE A 141
 None
 0.88A 3ko0M-1zmrA:
undetectable
3ko0P-1zmrA:
undetectable		 3ko0M-1zmrA:
14.14
3ko0P-1zmrA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 7 GLY A 340
GLY A 191
PHE A 369
PHE A 141
 None
 0.81A 3ko0M-1zmrA:
undetectable
3ko0P-1zmrA:
undetectable		 3ko0M-1zmrA:
14.14
3ko0P-1zmrA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 6 ILE A 207
ALA A 208
ALA A 301
THR A 303
 None
 1.04A 3mdrB-1zmrA:
undetectable		 3mdrB-1zmrA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 ALA A 328
ILE A 324
ILE A 356
VAL A 186
LEU A 298
 None
 1.16A 3ogpB-1zmrA:
undetectable		 3ogpB-1zmrA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 ILE A 329
VAL A 325
GLY A 190
ILE A 217
LEU A 294
 None
 0.72A 3ogpB-1zmrA:
undetectable		 3ogpB-1zmrA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 11 HIS A  59
ARG A  36
ILE A  37
VAL A  77
VAL A  31
 None
 1.26A 3rf4B-1zmrA:
undetectable
3rf4C-1zmrA:
undetectable		 3rf4B-1zmrA:
18.79
3rf4C-1zmrA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 7 TYR A 358
LEU A 166
ALA A 168
ASP A 139
 None
 1.12A 3rodD-1zmrA:
undetectable		 3rodD-1zmrA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		3 / 3 ARG A 258
PRO A 268
PHE A 318
 None
 1.00A 3thrC-1zmrA:
4.5		 3thrC-1zmrA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 8 ILE A 297
LEU A 298
VAL A 310
GLY A 214
 None
 0.67A 3w1wA-1zmrA:
2.5		 3w1wA-1zmrA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 11 VAL A 229
ALA A 223
LEU A 284
GLY A 215
PHE A 315
 None
 1.18A 3zosA-1zmrA:
undetectable
3zosB-1zmrA:
undetectable		 3zosA-1zmrA:
21.89
3zosB-1zmrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		3 / 3 LEU A  60
GLU A 110
SER A  58
 None
 0.72A 4ccqA-1zmrA:
1.9		 4ccqA-1zmrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.04A 4jksA-1zmrA:
3.0		 4jksA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.05A 4jksB-1zmrA:
3.0		 4jksB-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.02A 4jkuA-1zmrA:
undetectable		 4jkuA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.05A 4k8cB-1zmrA:
3.0		 4k8cB-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.04A 4k8kA-1zmrA:
3.7		 4k8kA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.03A 4k8kB-1zmrA:
3.0		 4k8kB-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.04A 4kahA-1zmrA:
3.4		 4kahA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.05A 4kahB-1zmrA:
3.9		 4kahB-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.04A 4kalB-1zmrA:
3.0		 4kalB-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.05A 4kanA-1zmrA:
3.2		 4kanA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.06A 4kanB-1zmrA:
3.1		 4kanB-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.04A 4kbeA-1zmrA:
undetectable		 4kbeA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.05A 4lbgA-1zmrA:
2.9		 4lbgA-1zmrA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ILE A 217
GLY A 215
GLY A 191
ILE A 188
ASP A 342
 None
 1.05A 4lcaB-1zmrA:
3.0		 4lcaB-1zmrA:
23.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		8 / 12 GLY A 191
GLY A 215
GLY A 216
LEU A 233
PHE A 263
LEU A 284
GLY A 311
VAL A 312
 None
 0.59A 4o33A-1zmrA:
46.5		 4o33A-1zmrA:
39.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		8 / 12 GLY A 191
GLY A 215
GLY A 216
LEU A 233
PHE A 263
LEU A 284
GLY A 311
VAL A 312
 None
 0.53A 4o3fA-1zmrA:
24.3		 4o3fA-1zmrA:
39.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		3 / 3 THR A 143
ASN A 115
PHE A 114
 None
 0.46A 4pd9A-1zmrA:
undetectable		 4pd9A-1zmrA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 GLY A  29
GLU A  70
VAL A  26
SER A  73
LEU A  60
 None
 1.27A 4yb6A-1zmrA:
undetectable
4yb6E-1zmrA:
undetectable		 4yb6A-1zmrA:
23.57
4yb6E-1zmrA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 GLY A  29
GLU A  70
VAL A  26
SER A  73
LEU A  60
 None
 1.26A 4yb6B-1zmrA:
undetectable
4yb6C-1zmrA:
undetectable		 4yb6B-1zmrA:
23.57
4yb6C-1zmrA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 GLY A  29
GLU A  70
VAL A  26
SER A  73
LEU A  60
 None
 1.26A 4yb6C-1zmrA:
undetectable
4yb6F-1zmrA:
undetectable		 4yb6C-1zmrA:
23.57
4yb6F-1zmrA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 SER A  73
LEU A  60
GLY A  29
GLU A  70
VAL A  26
 None
 1.27A 4yb6A-1zmrA:
undetectable
4yb6D-1zmrA:
undetectable		 4yb6A-1zmrA:
23.57
4yb6D-1zmrA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 SER A  73
LEU A  60
GLY A  29
GLU A  70
VAL A  26
 None
 1.26A 4yb6D-1zmrA:
undetectable
4yb6E-1zmrA:
undetectable		 4yb6D-1zmrA:
23.57
4yb6E-1zmrA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 10 SER A  73
LEU A  60
GLY A  29
GLU A  70
VAL A  26
 None
 1.24A 4yb6B-1zmrA:
undetectable
4yb6F-1zmrA:
undetectable		 4yb6B-1zmrA:
23.57
4yb6F-1zmrA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		3 / 3 THR A  43
HIS A 152
LEU A 381
 None
 0.75A 5axdA-1zmrA:
4.4		 5axdA-1zmrA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		3 / 3 THR A  43
HIS A 152
LEU A 381
 None
 0.75A 5axdC-1zmrA:
4.2		 5axdC-1zmrA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ALA A 144
GLY A 142
GLY A 363
ALA A  20
LEU A 166
 None
 0.97A 5c0oG-1zmrA:
5.3		 5c0oG-1zmrA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		4 / 6 TYR A 358
GLY A 362
GLU A 170
ASP A  21
 None
 1.28A 5emlA-1zmrA:
undetectable		 5emlA-1zmrA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 VAL A 112
LEU A  60
VAL A  77
LEU A  81
ILE A  44
 None
 1.04A 5mugA-1zmrA:
undetectable		 5mugA-1zmrA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 9 VAL A 325
ILE A 304
LEU A 298
ASN A 307
ALA A 346
 None
 0.98A 5nunA-1zmrA:
undetectable		 5nunA-1zmrA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1zmr PHOSPHOGLYCERATE
KINASE
(Escherichia
coli) 		5 / 12 ALA A 346
VAL A 312
ASP A 285
GLY A 215
LEU A 294
 None
 1.19A 5x24A-1zmrA:
undetectable		 5x24A-1zmrA:
22.47