SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A 201
PRO A 197
THR A 199
 None
 0.83A 1a7yB-1zn6A:
undetectable		 1a7yB-1zn6A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		4 / 8 GLY A  63
TRP A  62
HIS A 173
VAL A 182
 None
None
SO4  A 302 (-4.2A)
None
 0.89A 1dbbH-1zn6A:
undetectable
1dbbL-1zn6A:
undetectable		 1dbbH-1zn6A:
20.41
1dbbL-1zn6A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A 201
PRO A 197
THR A 199
 None
 0.89A 1dscC-1zn6A:
undetectable		 1dscC-1zn6A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		4 / 8 ALA A 149
GLU A 151
ASP A 154
ILE A 153
 None
 0.92A 1p7lC-1zn6A:
undetectable		 1p7lC-1zn6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ALA A  20
GLY A 137
ILE A  39
ILE A 184
TYR A 208
 None
 1.10A 1x1aA-1zn6A:
undetectable		 1x1aA-1zn6A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A 199
THR A 201
PRO A 197
 None
 0.87A 209dC-1zn6A:
undetectable		 209dC-1zn6A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A 201
PRO A 197
THR A 199
 None
 0.82A 316dC-1zn6A:
undetectable		 316dC-1zn6A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 213
ALA A 215
PHE A 128
ASP A 117
ASP A 171
 None
 1.17A 3gwuA-1zn6A:
undetectable		 3gwuA-1zn6A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A  69
ALA A  77
LYS A  79
 None
 0.71A 6fgcA-1zn6A:
undetectable		 6fgcA-1zn6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 1zn6 PHAGE-RELATED
CONSERVED
HYPOTHETICAL PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 THR A  69
ALA A  77
LYS A  79
 None
 0.71A 6fgdA-1zn6A:
undetectable		 6fgdA-1zn6A:
20.20