SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zno'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.84A 1muiB-1znoA:
undetectable		 1muiB-1znoA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		4 / 7 LEU A  84
THR A  93
ALA A  95
SER A 108
 None
 0.90A 1tyrB-1znoA:
undetectable		 1tyrB-1znoA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.67A 2avoB-1znoA:
undetectable		 2avoB-1znoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.76A 2f8gA-1znoA:
undetectable		 2f8gA-1znoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.79A 2hs1B-1znoA:
undetectable		 2hs1B-1znoA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.83A 2hs2A-1znoA:
undetectable		 2hs2A-1znoA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.83A 2hs2B-1znoA:
undetectable		 2hs2B-1znoA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.68A 2ienA-1znoA:
undetectable		 2ienA-1znoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.89A 2pymB-1znoA:
undetectable		 2pymB-1znoA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.79A 2qakB-1znoA:
undetectable		 2qakB-1znoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.82A 2qhcB-1znoA:
undetectable		 2qhcB-1znoA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		3 / 3 SER A 160
TYR A 163
HIS A 164
 None
 0.38A 2r2vD-1znoA:
undetectable		 2r2vD-1znoA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.75A 2r5pB-1znoA:
undetectable		 2r5pB-1znoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.76A 2r5pD-1znoA:
undetectable		 2r5pD-1znoA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.82A 2z54A-1znoA:
undetectable		 2z54A-1znoA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.83A 2z54B-1znoA:
undetectable		 2z54B-1znoA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.75A 3d1zA-1znoA:
undetectable		 3d1zA-1znoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.80A 3d20A-1znoA:
undetectable		 3d20A-1znoA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.74A 3ndtB-1znoA:
undetectable		 3ndtB-1znoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		5 / 12 ARG A  74
GLY A  77
ALA A  78
VAL A  44
ILE A  14
 None
 0.80A 3tkwA-1znoA:
undetectable		 3tkwA-1znoA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		4 / 5 VAL A 119
ARG A 122
MET A 133
GLU A 135
 None
 1.06A 4hojA-1znoA:
undetectable		 4hojA-1znoA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1zno HYPOTHETICAL UPF0244
PROTEIN VC0702
(Vibrio
cholerae) 		3 / 3 LEU A  65
GLY A  83
PHE A 174
 None
 0.57A 6exiC-1znoA:
undetectable		 6exiC-1znoA:
19.10