SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1zo2 NUCLEAR TRANSPORT
FACTOR 2
(Cryptosporidium
parvum) 		4 / 6 LEU A  42
TRP A  44
LEU A  62
PHE A  25
 None
 0.91A 1ru9H-1zo2A:
undetectable
1ru9L-1zo2A:
undetectable		 1ru9H-1zo2A:
18.64
1ru9L-1zo2A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1zo2 NUCLEAR TRANSPORT
FACTOR 2
(Cryptosporidium
parvum) 		4 / 6 LEU A  42
TRP A  44
LEU A  62
PHE A  25
 None
 0.95A 1rukH-1zo2A:
undetectable
1rukL-1zo2A:
undetectable		 1rukH-1zo2A:
18.64
1rukL-1zo2A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1zo2 NUCLEAR TRANSPORT
FACTOR 2
(Cryptosporidium
parvum) 		4 / 8 GLN A 104
ILE A 118
LEU A  35
THR A  24
 None
 0.76A 2xfhA-1zo2A:
undetectable		 2xfhA-1zo2A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 1zo2 NUCLEAR TRANSPORT
FACTOR 2
(Cryptosporidium
parvum) 		4 / 8 TYR A  21
PHE A  69
TYR A  22
LEU A  42
 None
 0.89A 3l4dA-1zo2A:
undetectable		 3l4dA-1zo2A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 1zo2 NUCLEAR TRANSPORT
FACTOR 2
(Cryptosporidium
parvum) 		4 / 8 PHE A  69
ILE A  71
PHE A 102
PHE A 106
 None
 0.71A 5x23A-1zo2A:
undetectable		 5x23A-1zo2A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_C_PCFC607_0
(CYTOCHROME B)		 1zo2 NUCLEAR TRANSPORT
FACTOR 2
(Cryptosporidium
parvum) 		5 / 10 TYR A  22
TYR A  21
PHE A  69
PHE A 102
VAL A  92
 None
 1.46A 6hu9C-1zo2A:
undetectable		 6hu9C-1zo2A:
16.06