SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zoq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		3 / 3 GLU A 310
HIS A 290
ASP A 314
 None
 0.69A 1i9gA-1zoqA:
undetectable		 1i9gA-1zoqA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		5 / 8 ALA A 283
LEU A 272
LEU A 228
VAL A 206
ILE A 220
 None
 1.39A 2uxpA-1zoqA:
undetectable		 2uxpA-1zoqA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		4 / 7 PRO A 223
ILE A 220
PRO A 239
GLY A 240
 None
 1.00A 2y7kA-1zoqA:
undetectable		 2y7kA-1zoqA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		4 / 8 GLN A 214
GLN A 217
GLU A 205
THR A 207
 None
 0.93A 3rglA-1zoqA:
undetectable		 3rglA-1zoqA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		6 / 12 GLY A 271
GLY A 270
GLY A 269
LEU A 228
ALA A 273
VAL A 311
 None
 1.45A 4htfA-1zoqA:
undetectable		 4htfA-1zoqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		5 / 12 GLY A 271
GLY A 270
GLY A 269
SER A 231
VAL A 365
 None
 0.99A 4htfB-1zoqA:
undetectable		 4htfB-1zoqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		3 / 3 GLU A 310
HIS A 290
ASP A 314
 None
 0.64A 5c0oG-1zoqA:
undetectable		 5c0oG-1zoqA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_2
(TUBULIN BETA-2B
CHAIN)		 1zoq INTERFERON
REGULATORY FACTOR 3
(Homo
sapiens) 		3 / 3 LEU A 322
LEU A 372
ARG A 338
 None
 0.60A 5hnzB-1zoqA:
undetectable		 5hnzB-1zoqA:
17.57