SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK1_A_T44A3003_1 (SERUM ALBUMIN)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 6	HIS A 164 ILE A 161 ALA A 81 VAL A 171	None	0.90A	1hk1A-1zosA: undetectable	1hk1A-1zosA: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JDV_A_ADNA1260_1 (5'-METHYLTHIOADENOSI NE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 10	VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.75A	1jdvA-1zosA: 22.1 1jdvD-1zosA: 22.1	1jdvA-1zosA: 24.81 1jdvD-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JDV_B_ADNB2260_1 (5'-METHYLTHIOADENOSI NE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 10	VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.74A	1jdvB-1zosA: 21.9 1jdvC-1zosA: 9.8	1jdvB-1zosA: 24.81 1jdvC-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JDV_D_ADND3260_1 (5'-METHYLTHIOADENOSI NE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 10	VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.75A	1jdvA-1zosA: 22.1 1jdvD-1zosA: 22.1	1jdvA-1zosA: 24.81 1jdvD-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JDV_E_ADNE4260_1 (5'-METHYLTHIOADENOSI NE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 12	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.72A	1jdvE-1zosA: 22.0 1jdvF-1zosA: 21.5	1jdvE-1zosA: 24.81 1jdvF-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_A_ADNA1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.48A	1odiA-1zosA: 23.4	1odiA-1zosA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_B_ADNB1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.59A	1odiB-1zosA: 23.7	1odiB-1zosA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_C_ADNC1238_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.57A	1odiC-1zosA: 23.4	1odiC-1zosA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_D_ADND1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.58A	1odiD-1zosA: 23.7	1odiD-1zosA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_E_ADNE1237_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.60A	1odiE-1zosA: 23.6	1odiE-1zosA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ODI_F_ADNF1238_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.58A	1odiF-1zosA: 23.4	1odiF-1zosA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK7_A_ADNA1245_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 9	SER A 76 GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.69A	1pk7A-1zosA: 22.7	1pk7A-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK7_B_ADNB1246_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 8	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.71A	1pk7B-1zosA: 22.7	1pk7B-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK7_C_ADNC1247_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	8 / 10	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.56A	1pk7C-1zosA: 23.5	1pk7C-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK9_A_2FAA306_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	8 / 10	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.55A	1pk9A-1zosA: 22.7	1pk9A-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK9_B_2FAB307_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 9	SER A 76 GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.56A	1pk9B-1zosA: 22.7	1pk9B-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PK9_C_2FAC308_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	8 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.45A	1pk9C-1zosA: 23.8	1pk9C-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PW7_A_RABA645_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 10	SER A 76 GLY A 78 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.64A	1pw7A-1zosA: 22.8	1pw7A-1zosA: 25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PW7_B_RABB646_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 9	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.57A	1pw7B-1zosA: 23.0	1pw7B-1zosA: 25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PW7_C_RABC647_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 9	SER A 76 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.61A	1pw7C-1zosA: 23.4	1pw7C-1zosA: 25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RBP_A_RTLA183_0 (PLASMA RETINOL-BINDING PROTEIN PRECURSOR)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 12	LEU A 190 ALA A 79 ALA A 81 ALA A 170 LEU A 95	None	1.33A	1rbpA-1zosA: undetectable	1rbpA-1zosA: 22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SH9_B_RITB301_1 (POL POLYPROTEIN)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 8	ALA A 56 ILE A 178 ILE A 6 GLY A 49 ILE A 50	None None None None MTM A 301 (-4.0A)	1.20A	1sh9A-1zosA: undetectable	1sh9A-1zosA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VHW_A_ADNA252_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.56A	1vhwA-1zosA: 23.0 1vhwD-1zosA: 22.9	1vhwA-1zosA: 24.81 1vhwD-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VHW_B_ADNB252_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 GLY A 78 VAL A 171 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.44A	1vhwB-1zosA: 23.2 1vhwF-1zosA: 23.0	1vhwB-1zosA: 24.81 1vhwF-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VHW_C_ADNC252_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.56A	1vhwC-1zosA: 23.0 1vhwE-1zosA: 23.0	1vhwC-1zosA: 24.81 1vhwE-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VHW_D_ADND252_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.56A	1vhwA-1zosA: 23.0 1vhwD-1zosA: 22.8	1vhwA-1zosA: 24.81 1vhwD-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VHW_E_ADNE252_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.56A	1vhwC-1zosA: 23.0 1vhwE-1zosA: 23.0	1vhwC-1zosA: 24.81 1vhwE-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VHW_F_ADNF252_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 10	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.56A	1vhwB-1zosA: 23.2 1vhwF-1zosA: 23.0	1vhwB-1zosA: 24.81 1vhwF-1zosA: 24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z35_A_2FAA300_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 10	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.72A	1z35A-1zosA: 22.3	1z35A-1zosA: 24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z37_A_ADNA300_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 9	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.66A	1z37A-1zosA: 22.3	1z37A-1zosA: 24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AC7_A_ADNA1216_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 11	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.60A	2ac7A-1zosA: 22.0 2ac7B-1zosA: 21.9	2ac7A-1zosA: 26.72 2ac7B-1zosA: 26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AC7_B_ADNB1215_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 11	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.61A	2ac7A-1zosA: 22.0 2ac7B-1zosA: 21.9	2ac7A-1zosA: 26.72 2ac7B-1zosA: 26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM9_A_ACAA502_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 8	MET A 9 ALA A 8 GLY A 49 ILE A 50	MTM A 301 ( 4.6A) MTM A 301 (-3.4A) None MTM A 301 (-4.0A)	0.91A	2zm9A-1zosA: undetectable	2zm9A-1zosA: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AF0_A_PAUA314_0 (PANTOTHENATE KINASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 8	LYS A 52 GLY A 51 HIS A 98 TYR A 97	None	0.87A	3af0A-1zosA: undetectable	3af0A-1zosA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKP_B_478B200_1 (PROTEASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 8	LEU A 222 GLY A 75 GLY A 175 ILE A 178 ILE A 192	None	1.08A	3ekpA-1zosA: undetectable	3ekpA-1zosA: 17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_A_ADNA251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.79A	3u40A-1zosA: 22.3 3u40F-1zosA: 21.8	3u40A-1zosA: 27.41 3u40F-1zosA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_B_ADNB251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 10	SER A 76 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.74A	3u40B-1zosA: 22.4 3u40C-1zosA: 22.3	3u40B-1zosA: 27.41 3u40C-1zosA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_C_ADNC251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 12	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.66A	3u40B-1zosA: 22.4 3u40C-1zosA: 22.3	3u40B-1zosA: 27.41 3u40C-1zosA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_D_ADND251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.65A	3u40D-1zosA: 22.6 3u40E-1zosA: 22.2	3u40D-1zosA: 27.41 3u40E-1zosA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_E_ADNE251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 12	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.63A	3u40D-1zosA: 22.6 3u40E-1zosA: 22.2	3u40D-1zosA: 27.41 3u40E-1zosA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U40_F_ADNF251_1 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 10	SER A 76 VAL A 171 GLU A 172 MET A 173 GLU A 174 ASP A 197	MTM A 301 (-3.1A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-2.9A)	0.94A	3u40A-1zosA: 22.3 3u40F-1zosA: 21.8	3u40A-1zosA: 27.41 3u40F-1zosA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UAW_A_ADNA236_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 11	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.56A	3uawA-1zosA: 22.8	3uawA-1zosA: 26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UAY_A_ADNA236_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 10	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.61A	3uayA-1zosA: 22.6	3uayA-1zosA: 26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D9H_A_ADNA301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.68A	4d9hA-1zosA: 22.8	4d9hA-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D9H_A_ADNA301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	SER A 76 GLY A 78 VAL A 171 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.83A	4d9hA-1zosA: 22.8	4d9hA-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DA6_A_GA2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 GLY A 78 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.1A) MTM A 301 (-3.6A) MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.60A	4da6A-1zosA: 22.4	4da6A-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DA6_A_GA2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 GLY A 78 VAL A 171 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.62A	4da6A-1zosA: 22.4	4da6A-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DA7_A_AC2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 10	GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.69A	4da7A-1zosA: 22.8	4da7A-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAN_A_2FAA301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.66A	4danA-1zosA: 22.3	4danA-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAN_A_2FAA301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.90A	4danA-1zosA: 22.3	4danA-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAN_B_2FAB301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	8 / 12	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196 ASP A 197	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A) MTM A 301 (-2.9A)	0.87A	4danA-1zosA: 22.3 4danB-1zosA: 22.6	4danA-1zosA: 24.06 4danB-1zosA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_A_ACTA304_0 (GLUTATHIONE TRANSFERASE GTE1)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 5	ALA A 7 ILE A 192 LEU A 222 ASN A 73	None	0.97A	4g19A-1zosA: undetectable	4g19A-1zosA: 23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IMA_D_ADND604_1 (PYRUVATE KINASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	3 / 3	ARG A 193 GLU A 174 ASN A 73	MTM A 301 (-3.2A) MTM A 301 (-2.6A) None	0.78A	4imaD-1zosA: undetectable	4imaD-1zosA: 19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JLT_A_8PRA505_1 (CYTOCHROME P450 2B4)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 8	ILE A 91 ILE A 145 ALA A 77 VAL A 221	None None MTM A 301 (-4.9A) None	0.81A	4jltA-1zosA: undetectable	4jltA-1zosA: 18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_D_SORD1343_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 5	ALA A 170 ARG A 193 HIS A 98 ALA A 146	None MTM A 301 (-3.2A) None None	1.13A	5a06C-1zosA: 2.6 5a06D-1zosA: undetectable	5a06C-1zosA: 22.94 5a06D-1zosA: 22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ALB_L_TIQL1210_2 (MEDI2452 LIGHT CHAIN)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 8	SER A 55 GLY A 51 ALA A 146 GLY A 148	None	0.80A	5albL-1zosA: undetectable	5albL-1zosA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_1_BEZ1801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	3 / 3	LEU A 71 PHE A 125 ILE A 3	None	0.66A	5dzk1-1zosA: undetectable 5dzkF-1zosA: undetectable 5dzkM-1zosA: undetectable	5dzk1-1zosA: 0.90 5dzkF-1zosA: 24.71 5dzkM-1zosA: 25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3C_A_AC2A301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 GLY A 78 VAL A 171 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.33A	5i3cA-1zosA: 22.9	5i3cA-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3C_B_AC2B301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	6 / 10	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A)	0.51A	5i3cB-1zosA: 23.4	5i3cB-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3C_C_AC2C301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 11	SER A 76 ALA A 92 VAL A 90 SER A 196 ILE A 84	MTM A 301 (-3.1A) None None MTM A 301 (-3.4A) None	1.24A	5i3cC-1zosA: 23.0	5i3cC-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3C_C_AC2C301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	7 / 11	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173 GLU A 174 SER A 196	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A) MTM A 301 (-2.6A) MTM A 301 (-3.4A)	0.54A	5i3cC-1zosA: 23.0	5i3cC-1zosA: 25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	4 / 6	VAL A 59 LEU A 190 ARG A 193 ILE A 91	None None MTM A 301 (-3.2A) None	0.98A	5jw1A-1zosA: undetectable	5jw1A-1zosA: 18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNC_A_QI9A301_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 GLY A 78 VAL A 171 GLU A 172 MET A 173	MTM A 301 (-3.1A) MTM A 301 (-3.6A) None None MTM A 301 (-3.5A)	0.58A	5zncA-1zosA: 21.6	5zncA-1zosA: 23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZNC_A_QI9A301_0 (PURINE NUCLEOSIDE PHOSPHORYLASE)	1zos	5'-METHYLTHIOADENOSI NE / S-ADENOSYLHOMOCYSTEI NE NUCLEOSIDASE (Streptococcus pneumoniae)	5 / 9	SER A 76 VAL A 171 GLU A 172 MET A 173 ASP A 197	MTM A 301 (-3.1A) None None MTM A 301 (-3.5A) MTM A 301 (-2.9A)	1.07A	5zncA-1zosA: 21.6	5zncA-1zosA: 23.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK1_A_T44A3003_1","SERUM ALBUMIN","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"HIS A 164;ILE A 161;ALA A  81;VAL A 171","None","0.90A","1hk1A-1zosA:undetectable","1hk1A-1zosA:16.08"],["1JDV_A_ADNA1260_1","5'-METHYLTHIOADENOSINE PHOSPHORYLASE;5'-METHYLTHIOADENOSINE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.75A","1jdvA-1zosA:22.1;1jdvD-1zosA:22.1","1jdvA-1zosA:24.81;1jdvD-1zosA:24.81"],["1JDV_B_ADNB2260_1","5'-METHYLTHIOADENOSINE PHOSPHORYLASE;5'-METHYLTHIOADENOSINE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.74A","1jdvB-1zosA:21.9;1jdvC-1zosA:9.8","1jdvB-1zosA:24.81;1jdvC-1zosA:24.81"],["1JDV_D_ADND3260_1","5'-METHYLTHIOADENOSINE PHOSPHORYLASE;5'-METHYLTHIOADENOSINE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.75A","1jdvA-1zosA:22.1;1jdvD-1zosA:22.1","1jdvA-1zosA:24.81;1jdvD-1zosA:24.81"],["1JDV_E_ADNE4260_1","5'-METHYLTHIOADENOSINE PHOSPHORYLASE;5'-METHYLTHIOADENOSINE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.72A","1jdvE-1zosA:22.0;1jdvF-1zosA:21.5","1jdvE-1zosA:24.81;1jdvF-1zosA:24.81"],["1ODI_A_ADNA1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.48A","1odiA-1zosA:23.4","1odiA-1zosA:25.91"],["1ODI_B_ADNB1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.59A","1odiB-1zosA:23.7","1odiB-1zosA:25.91"],["1ODI_C_ADNC1238_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.57A","1odiC-1zosA:23.4","1odiC-1zosA:25.91"],["1ODI_D_ADND1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.58A","1odiD-1zosA:23.7","1odiD-1zosA:25.91"],["1ODI_E_ADNE1237_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.60A","1odiE-1zosA:23.6","1odiE-1zosA:25.91"],["1ODI_F_ADNF1238_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.58A","1odiF-1zosA:23.4","1odiF-1zosA:25.91"],["1PK7_A_ADNA1245_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.69A","1pk7A-1zosA:22.7","1pk7A-1zosA:25.59"],["1PK7_B_ADNB1246_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.71A","1pk7B-1zosA:22.7","1pk7B-1zosA:25.59"],["1PK7_C_ADNC1247_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",8,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.56A","1pk7C-1zosA:23.5","1pk7C-1zosA:25.59"],["1PK9_A_2FAA306_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",8,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.55A","1pk9A-1zosA:22.7","1pk9A-1zosA:25.59"],["1PK9_B_2FAB307_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.56A","1pk9B-1zosA:22.7","1pk9B-1zosA:25.59"],["1PK9_C_2FAC308_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",8,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.45A","1pk9C-1zosA:23.8","1pk9C-1zosA:25.59"],["1PW7_A_RABA645_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.64A","1pw7A-1zosA:22.8","1pw7A-1zosA:25.39"],["1PW7_B_RABB646_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.57A","1pw7B-1zosA:23.0","1pw7B-1zosA:25.39"],["1PW7_C_RABC647_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.61A","1pw7C-1zosA:23.4","1pw7C-1zosA:25.39"],["1RBP_A_RTLA183_0","PLASMA RETINOL-BINDING PROTEIN PRECURSOR","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"LEU A 190;ALA A  79;ALA A  81;ALA A 170;LEU A  95","None","1.33A","1rbpA-1zosA:undetectable","1rbpA-1zosA:22.91"],["1SH9_B_RITB301_1","POL POLYPROTEIN;POL POLYPROTEIN","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"ALA A  56;ILE A 178;ILE A   6;GLY A  49;ILE A  50","None;None;None;None;MTM A 301 (-4.0A)","1.20A","1sh9A-1zosA:undetectable","1sh9A-1zosA:17.98"],["1VHW_A_ADNA252_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.56A","1vhwA-1zosA:23.0;1vhwD-1zosA:22.9","1vhwA-1zosA:24.81;1vhwD-1zosA:24.81"],["1VHW_B_ADNB252_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;GLY A  78;VAL A 171;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.44A","1vhwB-1zosA:23.2;1vhwF-1zosA:23.0","1vhwB-1zosA:24.81;1vhwF-1zosA:24.81"],["1VHW_C_ADNC252_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.56A","1vhwC-1zosA:23.0;1vhwE-1zosA:23.0","1vhwC-1zosA:24.81;1vhwE-1zosA:24.81"],["1VHW_D_ADND252_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.56A","1vhwA-1zosA:23.0;1vhwD-1zosA:22.8","1vhwA-1zosA:24.81;1vhwD-1zosA:24.81"],["1VHW_E_ADNE252_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.56A","1vhwC-1zosA:23.0;1vhwE-1zosA:23.0","1vhwC-1zosA:24.81;1vhwE-1zosA:24.81"],["1VHW_F_ADNF252_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.56A","1vhwB-1zosA:23.2;1vhwF-1zosA:23.0","1vhwB-1zosA:24.81;1vhwF-1zosA:24.81"],["1Z35_A_2FAA300_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.72A","1z35A-1zosA:22.3","1z35A-1zosA:24.35"],["1Z37_A_ADNA300_1","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.66A","1z37A-1zosA:22.3","1z37A-1zosA:24.35"],["2AC7_A_ADNA1216_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.60A","2ac7A-1zosA:22.0;2ac7B-1zosA:21.9","2ac7A-1zosA:26.72;2ac7B-1zosA:26.72"],["2AC7_B_ADNB1215_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.61A","2ac7A-1zosA:22.0;2ac7B-1zosA:21.9","2ac7A-1zosA:26.72;2ac7B-1zosA:26.72"],["2ZM9_A_ACAA502_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"MET A   9;ALA A   8;GLY A  49;ILE A  50","MTM A 301 ( 4.6A);MTM A 301 (-3.4A);None;MTM A 301 (-4.0A)","0.91A","2zm9A-1zosA:undetectable","2zm9A-1zosA:19.34"],["3AF0_A_PAUA314_0","PANTOTHENATE KINASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"LYS A  52;GLY A  51;HIS A  98;TYR A  97","None","0.87A","3af0A-1zosA:undetectable","3af0A-1zosA:23.08"],["3EKP_B_478B200_1","PROTEASE;PROTEASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"LEU A 222;GLY A  75;GLY A 175;ILE A 178;ILE A 192","None","1.08A","3ekpA-1zosA:undetectable","3ekpA-1zosA:17.90"],["3U40_A_ADNA251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.79A","3u40A-1zosA:22.3;3u40F-1zosA:21.8","3u40A-1zosA:27.41;3u40F-1zosA:27.41"],["3U40_B_ADNB251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.74A","3u40B-1zosA:22.4;3u40C-1zosA:22.3","3u40B-1zosA:27.41;3u40C-1zosA:27.41"],["3U40_C_ADNC251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.66A","3u40B-1zosA:22.4;3u40C-1zosA:22.3","3u40B-1zosA:27.41;3u40C-1zosA:27.41"],["3U40_D_ADND251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.65A","3u40D-1zosA:22.6;3u40E-1zosA:22.2","3u40D-1zosA:27.41;3u40E-1zosA:27.41"],["3U40_E_ADNE251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.63A","3u40D-1zosA:22.6;3u40E-1zosA:22.2","3u40D-1zosA:27.41;3u40E-1zosA:27.41"],["3U40_F_ADNF251_1","PURINE NUCLEOSIDE PHOSPHORYLASE;PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;VAL A 171;GLU A 172;MET A 173;GLU A 174;ASP A 197","MTM A 301 (-3.1A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-2.9A)","0.94A","3u40A-1zosA:22.3;3u40F-1zosA:21.8","3u40A-1zosA:27.41;3u40F-1zosA:27.41"],["3UAW_A_ADNA236_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.56A","3uawA-1zosA:22.8","3uawA-1zosA:26.72"],["3UAY_A_ADNA236_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.61A","3uayA-1zosA:22.6","3uayA-1zosA:26.72"],["4D9H_A_ADNA301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.68A","4d9hA-1zosA:22.8","4d9hA-1zosA:24.06"],["4D9H_A_ADNA301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;GLY A  78;VAL A 171;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.83A","4d9hA-1zosA:22.8","4d9hA-1zosA:24.06"],["4DA6_A_GA2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;GLY A  78;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.1A);MTM A 301 (-3.6A);MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.60A","4da6A-1zosA:22.4","4da6A-1zosA:24.06"],["4DA6_A_GA2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;GLY A  78;VAL A 171;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.62A","4da6A-1zosA:22.4","4da6A-1zosA:24.06"],["4DA7_A_AC2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.69A","4da7A-1zosA:22.8","4da7A-1zosA:24.06"],["4DAN_A_2FAA301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.66A","4danA-1zosA:22.3","4danA-1zosA:24.06"],["4DAN_A_2FAA301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.90A","4danA-1zosA:22.3","4danA-1zosA:24.06"],["4DAN_B_2FAB301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE;PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",8,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196;ASP A 197","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A);MTM A 301 (-2.9A)","0.87A","4danA-1zosA:22.3;4danB-1zosA:22.6","4danA-1zosA:24.06;4danB-1zosA:24.06"],["4G19_A_ACTA304_0","GLUTATHIONE TRANSFERASE GTE1","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"ALA A   7;ILE A 192;LEU A 222;ASN A  73","None","0.97A","4g19A-1zosA:undetectable","4g19A-1zosA:23.42"],["4IMA_D_ADND604_1","PYRUVATE KINASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",3,"ARG A 193;GLU A 174;ASN A  73","MTM A 301 (-3.2A);MTM A 301 (-2.6A);None","0.78A","4imaD-1zosA:undetectable","4imaD-1zosA:19.81"],["4JLT_A_8PRA505_1","CYTOCHROME P450 2B4","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"ILE A  91;ILE A 145;ALA A  77;VAL A 221","None;None;MTM A 301 (-4.9A);None","0.81A","4jltA-1zosA:undetectable","4jltA-1zosA:18.99"],["5A06_D_SORD1343_0","ALDOSE-ALDOSE OXIDOREDUCTASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"ALA A 170;ARG A 193;HIS A  98;ALA A 146","None;MTM A 301 (-3.2A);None;None","1.13A","5a06C-1zosA:2.6;5a06D-1zosA:undetectable","5a06C-1zosA:22.94;5a06D-1zosA:22.94"],["5ALB_L_TIQL1210_2","MEDI2452 LIGHT CHAIN","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"SER A  55;GLY A  51;ALA A 146;GLY A 148","None","0.80A","5albL-1zosA:undetectable","5albL-1zosA:21.65"],["5DZK_1_BEZ1801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1;ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",3,"LEU A  71;PHE A 125;ILE A   3","None","0.66A","5dzk1-1zosA:undetectable;5dzkF-1zosA:undetectable;5dzkM-1zosA:undetectable","5dzk1-1zosA:0.90;5dzkF-1zosA:24.71;5dzkM-1zosA:25.11"],["5I3C_A_AC2A301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;GLY A  78;VAL A 171;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.33A","5i3cA-1zosA:22.9","5i3cA-1zosA:25.59"],["5I3C_B_AC2B301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",6,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A)","0.51A","5i3cB-1zosA:23.4","5i3cB-1zosA:25.59"],["5I3C_C_AC2C301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;ALA A  92;VAL A  90;SER A 196;ILE A  84","MTM A 301 (-3.1A);None;None;MTM A 301 (-3.4A);None","1.24A","5i3cC-1zosA:23.0","5i3cC-1zosA:25.59"],["5I3C_C_AC2C301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",7,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173;GLU A 174;SER A 196","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.6A);MTM A 301 (-3.4A)","0.54A","5i3cC-1zosA:23.0","5i3cC-1zosA:25.59"],["5JW1_A_CELA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",4,"VAL A  59;LEU A 190;ARG A 193;ILE A  91","None;None;MTM A 301 (-3.2A);None","0.98A","5jw1A-1zosA:undetectable","5jw1A-1zosA:18.68"],["5ZNC_A_QI9A301_0","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;GLY A  78;VAL A 171;GLU A 172;MET A 173","MTM A 301 (-3.1A);MTM A 301 (-3.6A);None;None;MTM A 301 (-3.5A)","0.58A","5zncA-1zosA:21.6","5zncA-1zosA:23.22"],["5ZNC_A_QI9A301_0","PURINE NUCLEOSIDE PHOSPHORYLASE","1zos","5'-METHYLTHIOADENOSINE \/ S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE","Streptococcus pneumoniae",5,"SER A  76;VAL A 171;GLU A 172;MET A 173;ASP A 197","MTM A 301 (-3.1A);None;None;MTM A 301 (-3.5A);MTM A 301 (-2.9A)","1.07A","5zncA-1zosA:21.6","5zncA-1zosA:23.22"]]