SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		3 / 3 THR A 356
LEU A 357
LEU A 197
 None
 0.61A 1mz9C-1zovA:
undetectable		 1mz9C-1zovA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 LEU A  71
GLY A  15
GLY A  19
TYR A  20
TYR A  21
 None
 1.08A 1p91B-1zovA:
undetectable		 1p91B-1zovA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		4 / 8 TYR A 253
GLU A 249
VAL A 101
TYR A  92
 None
 1.08A 2fl5E-1zovA:
undetectable
2fl5F-1zovA:
undetectable		 2fl5E-1zovA:
19.44
2fl5F-1zovA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		4 / 8 GLY A  19
VAL A   6
VAL A  27
GLN A  25
 None
 0.76A 3fi0B-1zovA:
undetectable		 3fi0B-1zovA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		4 / 8 GLY A  19
VAL A   6
VAL A  27
GLN A  25
 None
 0.75A 3fi0I-1zovA:
undetectable		 3fi0I-1zovA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 ALA A 138
GLY A  93
SER A 102
GLY A 120
GLU A 119
 None
 0.96A 3g2oA-1zovA:
3.0		 3g2oA-1zovA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 GLY A 263
MET A 302
THR A  87
VAL A 146
PHE A 259
 None
 1.30A 3gn8B-1zovA:
0.0		 3gn8B-1zovA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		3 / 3 GLY A 341
THR A 318
ASN A 205
 None
 0.45A 3v4tD-1zovA:
undetectable		 3v4tD-1zovA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 TYR A 235
ALA A 128
THR A 124
LEU A  90
TYR A  92
 None
 1.12A 4g1bA-1zovA:
4.4		 4g1bA-1zovA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 GLY A 263
LEU A 298
MET A 302
THR A  87
PHE A 259
 None
 1.43A 4p6xG-1zovA:
undetectable		 4p6xG-1zovA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 GLY A 263
LEU A 298
MET A 302
THR A  87
PHE A 259
 None
 1.43A 4p6xI-1zovA:
undetectable		 4p6xI-1zovA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		4 / 4 GLY A 312
VAL A 224
PHE A 297
ILE A 266
 None
 1.17A 4xv2B-1zovA:
undetectable		 4xv2B-1zovA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 8 ALA A  11
VAL A 167
GLY A  15
ALA A  18
GLY A  19
 None
 1.41A 4zjzB-1zovA:
undetectable		 4zjzB-1zovA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		4 / 8 PRO A  38
LEU A  75
ILE A  83
LEU A  31
 None
 0.90A 5ieoA-1zovA:
undetectable		 5ieoA-1zovA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_A_ACTA301_0
(ANTIBODY FAB HEAVY
CHAIN)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		4 / 4 THR A  85
VAL A 146
PRO A 257
THR A  87
 None
 1.42A 5mthA-1zovA:
0.0
5mthH-1zovA:
0.0		 5mthA-1zovA:
21.00
5mthH-1zovA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 9 LEU A 218
VAL A 214
LEU A 209
ILE A 327
PRO A 331
 None
 1.14A 5og9A-1zovA:
undetectable		 5og9A-1zovA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		5 / 12 LEU A 218
VAL A 214
LEU A 209
ILE A 327
PRO A 331
 None
 1.15A 5og9B-1zovA:
undetectable		 5og9B-1zovA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 1zov MONOMERIC SARCOSINE
OXIDASE
(Bacillus
sp.
NS-129) 		6 / 12 GLY A  88
THR A  87
GLY A 145
PRO A 242
LEU A 117
ASN A 143
 None
 1.38A 5ybbA-1zovA:
undetectable		 5ybbA-1zovA:
21.95