SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A7Q_A_CFBA328_2 (DEOXYCYTIDINE KINASE)	1zp2	RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT (Schizosaccharomy ces pombe)	4 / 4	ILE A 118 ASP A 105 LEU A 109 ARG A 115	None	1.44A	2a7qA-1zp2A: undetectable	2a7qA-1zp2A: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZV_B_AZMB263_1 (CARBONIC ANHYDRASE 13)	1zp2	RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT (Schizosaccharomy ces pombe)	5 / 10	HIS A 137 VAL A 89 LEU A 59 THR A 55 VAL A 58	None	1.36A	3czvB-1zp2A: undetectable	3czvB-1zp2A: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BYK_A_OAQA302_0 (SULFOTRANSFERASE)	1zp2	RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT (Schizosaccharomy ces pombe)	5 / 12	PRO A 138 ILE A 203 LEU A 180 LEU A 200 THR A 195	None	1.31A	5bykA-1zp2A: undetectable	5bykA-1zp2A: 22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA826_0 (GEPHYRIN)	1zp2	RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT (Schizosaccharomy ces pombe)	3 / 3	HIS A 95 ARG A 115 ILE A 96	None	0.83A	6fgdA-1zp2A: undetectable	6fgdA-1zp2A: 18.89

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A7Q_A_CFBA328_2","DEOXYCYTIDINE KINASE","1zp2","RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT","Schizosaccharomyces pombe",4,"ILE A 118;ASP A 105;LEU A 109;ARG A 115","None","1.44A","2a7qA-1zp2A:undetectable","2a7qA-1zp2A:22.06"],["3CZV_B_AZMB263_1","CARBONIC ANHYDRASE 13","1zp2","RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT","Schizosaccharomyces pombe",5,"HIS A 137;VAL A  89;LEU A  59;THR A  55;VAL A  58","None","1.36A","3czvB-1zp2A:undetectable","3czvB-1zp2A:21.23"],["5BYK_A_OAQA302_0","SULFOTRANSFERASE","1zp2","RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT","Schizosaccharomyces pombe",5,"PRO A 138;ILE A 203;LEU A 180;LEU A 200;THR A 195","None","1.31A","5bykA-1zp2A:undetectable","5bykA-1zp2A:22.30"],["6FGD_A_ACTA826_0","GEPHYRIN","1zp2","RNA POLYMERASE II HOLOENZYME CYCLIN-LIKE SUBUNIT","Schizosaccharomyces pombe",3,"HIS A  95;ARG A 115;ILE A  96","None","0.83A","6fgdA-1zp2A:undetectable","6fgdA-1zp2A:18.89"]]