SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zp6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		4 / 8 ALA A 138
ALA A 119
SER A  20
GLY A  16
 None
None
SO4  A 201 (-3.4A)
None
 0.78A 2vh3B-1zp6A:
undetectable		 2vh3B-1zp6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		5 / 11 SER A  20
PHE A 144
ASP A  43
LEU A  13
SER A  15
 SO4  A 201 (-3.4A)
None
None
None
None
 1.46A 3ko0Q-1zp6A:
0.0
3ko0R-1zp6A:
undetectable
3ko0S-1zp6A:
0.0
3ko0T-1zp6A:
undetectable		 3ko0Q-1zp6A:
19.37
3ko0R-1zp6A:
19.37
3ko0S-1zp6A:
19.37
3ko0T-1zp6A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		3 / 3 ALA A  28
ASN A  31
LEU A  32
 None
 0.31A 5i1nC-1zp6A:
undetectable		 5i1nC-1zp6A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		3 / 3 ALA A  28
ASN A  31
LEU A  32
 None
 0.18A 5i1oC-1zp6A:
undetectable		 5i1oC-1zp6A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		3 / 3 ALA A  28
ASN A  31
LEU A  32
 None
 0.43A 5i1oA-1zp6A:
undetectable		 5i1oA-1zp6A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		3 / 3 ALA A  28
ASN A  31
LEU A  32
 None
 0.32A 5i1pA-1zp6A:
undetectable		 5i1pA-1zp6A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		3 / 3 ALA A  28
ASN A  31
LEU A  32
 None
 0.20A 5i1pD-1zp6A:
undetectable		 5i1pD-1zp6A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		4 / 7 HIS A 141
ILE A 120
VAL A 137
ARG A 126
 None
None
None
SO4  A 201 (-3.3A)
 1.30A 5kkzC-1zp6A:
undetectable
5kkzE-1zp6A:
undetectable		 5kkzC-1zp6A:
22.77
5kkzE-1zp6A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1zp6 HYPOTHETICAL PROTEIN
ATU3015
(Agrobacterium
fabrum) 		4 / 7 HIS A 141
ILE A 120
VAL A 137
ARG A 126
 None
None
None
SO4  A 201 (-3.3A)
 1.27A 5kkzM-1zp6A:
undetectable
5kkzO-1zp6A:
undetectable		 5kkzM-1zp6A:
22.77
5kkzO-1zp6A:
18.10