SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
4 / 7 ALA A  14
ILE A  74
ILE A 105
PHE A 185
None
0.78A 1upfB-1zq7A:
undetectable
1upfB-1zq7A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
4 / 5 LEU A  22
ALA A  78
ILE A  79
SER A  80
None
1.13A 2othA-1zq7A:
undetectable
2othA-1zq7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
5 / 9 LEU A 130
THR A 160
HIS A 159
ILE A 154
LEU A 157
None
1.30A 3hy7A-1zq7A:
undetectable
3hy7A-1zq7A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
4 / 5 ILE A 125
PRO A 147
LYS A 127
GLY A 126
None
0.86A 3tkdB-1zq7A:
undetectable
3tkdB-1zq7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
4 / 5 ILE A 125
PRO A 147
LYS A 127
GLY A 126
None
0.87A 3tkdA-1zq7A:
undetectable
3tkdA-1zq7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
3 / 3 ARG A  87
PHE A  88
PRO A  89
None
0.64A 3zoaB-1zq7A:
undetectable
3zoaB-1zq7A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
4 / 5 GLU A 110
PRO A 109
THR A 107
GLN A 108
None
1.24A 6fgdA-1zq7A:
undetectable
6fgdA-1zq7A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei)
4 / 5 LEU A 166
CYH A 161
THR A 160
GLY A 139
None
0.91A 6gtqA-1zq7A:
undetectable
6gtqA-1zq7A:
21.86