SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		4 / 6 PHE A 319
GLU A 285
LEU A 287
VAL A 255
 None
 0.96A 1hk1A-1zr5A:
undetectable		 1hk1A-1zr5A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		4 / 7 PHE A 319
GLU A 285
LEU A 287
VAL A 255
 None
 0.97A 1hk3A-1zr5A:
undetectable		 1hk3A-1zr5A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		3 / 3 LEU A 351
LEU A 184
MET A 364
 None
 0.77A 1ya3B-1zr5A:
undetectable		 1ya3B-1zr5A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 205
PHE A 181
VAL A 210
ALA A 308
 None
 1.01A 2cizA-1zr5A:
0.0		 2cizA-1zr5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 205
PHE A 181
VAL A 210
ALA A 308
 None
 0.99A 2j5mA-1zr5A:
0.0		 2j5mA-1zr5A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		5 / 11 GLY A 235
ALA A 206
GLY A 263
ILE A 328
LEU A 288
 None
 0.87A 4kt0A-1zr5A:
undetectable
4kt0J-1zr5A:
undetectable		 4kt0A-1zr5A:
14.88
4kt0J-1zr5A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		5 / 12 ALA A 268
ALA A 308
LEU A 205
HIS A 273
PHE A 239
 None
 1.29A 4zo1X-1zr5A:
undetectable		 4zo1X-1zr5A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 205
ASN A 317
LEU A 329
PHE A 349
ILE A 328
 None
 1.44A 5dv4A-1zr5A:
undetectable		 5dv4A-1zr5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1zr5 H2AFY PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 252
GLY A 251
ASN A 250
LYS A 249
 None
 1.04A 5xxiA-1zr5A:
undetectable		 5xxiA-1zr5A:
19.42