SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 LEU A 125
HIS A 127
THR A 113
LEU A 110
PHE A 200
 None
 1.46A 1d4fA-1zr6A:
undetectable		 1d4fA-1zr6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 LEU A 125
THR A 113
LEU A 110
GLY A 134
PHE A 200
 None
None
None
FAD  A 501 (-3.3A)
None
 1.34A 1d4fA-1zr6A:
undetectable		 1d4fA-1zr6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 HIS A 127
THR A 113
LEU A 110
GLY A 134
PHE A 200
 None
None
None
FAD  A 501 (-3.3A)
None
 1.49A 1d4fD-1zr6A:
undetectable		 1d4fD-1zr6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 LEU A 125
HIS A 127
THR A 113
LEU A 110
GLY A 134
 None
None
None
None
FAD  A 501 (-3.3A)
 1.33A 1d4fD-1zr6A:
undetectable		 1d4fD-1zr6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 7 VAL A 195
VAL A  53
ILE A 170
LEU A  57
 FAD  A 501 (-3.8A)
None
None
None
 1.02A 1iepB-1zr6A:
undetectable		 1iepB-1zr6A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 VAL A 411
ILE A 414
TRP A 354
LEU A 253
 None
 1.19A 1j96A-1zr6A:
undetectable		 1j96A-1zr6A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 TRP A 255
ALA A 229
LEU A 253
ALA A 277
 None
 1.33A 2jstA-1zr6A:
undetectable
2jstB-1zr6A:
undetectable		 2jstA-1zr6A:
10.51
2jstB-1zr6A:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 4 PRO A 324
ASP A 378
ASP A 370
ASP A 421
 None
 1.31A 2nyuA-1zr6A:
undetectable		 2nyuA-1zr6A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 PHE A 198
PHE A 200
GLY A 142
GLY A 143
 None
None
None
FAD  A 501 ( 3.9A)
 0.84A 2qr2A-1zr6A:
undetectable
2qr2B-1zr6A:
undetectable		 2qr2A-1zr6A:
18.90
2qr2B-1zr6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 GLY A 142
GLY A 143
PHE A 198
PHE A 200
 None
FAD  A 501 ( 3.9A)
None
None
 0.83A 2qr2A-1zr6A:
undetectable
2qr2B-1zr6A:
undetectable		 2qr2A-1zr6A:
18.90
2qr2B-1zr6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 8 PHE A 198
PHE A 200
GLY A 142
GLY A 143
 None
None
None
FAD  A 501 ( 3.9A)
 0.80A 2qx4A-1zr6A:
undetectable
2qx4B-1zr6A:
undetectable		 2qx4A-1zr6A:
18.90
2qx4B-1zr6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 PHE A 198
PHE A 200
GLY A 142
GLY A 143
 None
None
None
FAD  A 501 ( 3.9A)
 0.82A 2qx6A-1zr6A:
undetectable
2qx6B-1zr6A:
undetectable		 2qx6A-1zr6A:
18.90
2qx6B-1zr6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		3 / 3 PRO A 398
GLY A 403
TYR A 399
 None
 0.72A 2vouA-1zr6A:
undetectable		 2vouA-1zr6A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 LEU A 158
LEU A 153
GLY A 143
PHE A 182
VAL A 133
 None
None
FAD  A 501 ( 3.9A)
None
FAD  A 501 (-4.2A)
 1.30A 2w8yA-1zr6A:
undetectable		 2w8yA-1zr6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 10 THR A 432
VAL A  33
PHE A 316
ASN A 428
ALA A 318
 None
None
None
FAD  A 501 (-3.2A)
None
 1.37A 2x2iB-1zr6A:
0.0		 2x2iB-1zr6A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 ILE A 306
GLY A  68
ALA A 132
LEU A 110
ALA A  65
 None
FAD  A 501 (-3.1A)
None
None
FAD  A 501 (-3.8A)
 1.04A 2yvlA-1zr6A:
undetectable		 2yvlA-1zr6A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 ILE A 306
GLY A  68
ALA A 132
LEU A 110
ALA A  65
 None
FAD  A 501 (-3.1A)
None
None
FAD  A 501 (-3.8A)
 1.04A 2yvlC-1zr6A:
undetectable		 2yvlC-1zr6A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 7 GLU A 461
ALA A 474
PRO A 460
ALA A 456
 None
 1.11A 2zgwA-1zr6A:
undetectable		 2zgwA-1zr6A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 GLU A 461
ALA A 474
PRO A 460
ALA A 456
 None
 1.10A 2zgwB-1zr6A:
1.2		 2zgwB-1zr6A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.47A 3ablA-1zr6A:
0.6
3ablB-1zr6A:
0.0
3ablT-1zr6A:
0.0		 3ablA-1zr6A:
21.86
3ablB-1zr6A:
17.47
3ablT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.45A 3ag1A-1zr6A:
0.0
3ag1B-1zr6A:
0.0
3ag1T-1zr6A:
0.0		 3ag1A-1zr6A:
21.86
3ag1B-1zr6A:
17.47
3ag1T-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.45A 3ag3A-1zr6A:
0.0
3ag3B-1zr6A:
0.0
3ag3T-1zr6A:
0.0		 3ag3A-1zr6A:
21.86
3ag3B-1zr6A:
17.47
3ag3T-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		3 / 3 ASN A  30
ASP A 431
GLN A 408
 None
 0.84A 3eeyD-1zr6A:
undetectable		 3eeyD-1zr6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 10 LEU A 125
HIS A 127
THR A 113
GLY A 134
PHE A 200
 None
None
None
FAD  A 501 (-3.3A)
None
 1.50A 3h9uA-1zr6A:
undetectable		 3h9uA-1zr6A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 GLY A  67
LYS A  66
GLU A  87
GLY A  69
 FAD  A 501 (-3.5A)
None
None
FAD  A 501 (-3.1A)
 0.81A 3onnA-1zr6A:
undetectable		 3onnA-1zr6A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 TYR A 298
GLY A 145
ALA A 147
ASN A 258
TYR A 212
 None
FAD  A 501 ( 4.9A)
None
None
None
 1.45A 3s8pA-1zr6A:
undetectable		 3s8pA-1zr6A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 HIS A 127
SER A 126
THR A 148
ASP A 290
 None
 1.16A 3tm4A-1zr6A:
undetectable		 3tm4A-1zr6A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 HIS A 127
SER A 126
THR A 148
ASP A 290
 None
 1.14A 3tm4B-1zr6A:
undetectable		 3tm4B-1zr6A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.42A 3wg7A-1zr6A:
0.5
3wg7B-1zr6A:
0.0
3wg7T-1zr6A:
0.0		 3wg7A-1zr6A:
21.86
3wg7B-1zr6A:
17.47
3wg7T-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 TRP A 183
GLY A 446
ALA A 375
PHE A 192
 None
 1.18A 3wqwA-1zr6A:
undetectable		 3wqwA-1zr6A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.45A 3x2qA-1zr6A:
0.0
3x2qB-1zr6A:
0.0
3x2qT-1zr6A:
0.0		 3x2qA-1zr6A:
21.86
3x2qB-1zr6A:
17.47
3x2qT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 TYR A 298
GLY A 145
ALA A 147
ASN A 258
TYR A 212
 None
FAD  A 501 ( 4.9A)
None
None
None
 1.44A 4bupA-1zr6A:
undetectable		 4bupA-1zr6A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 LEU A 117
GLY A 107
GLY A 106
THR A 113
GLY A 137
 None
None
FAD  A 501 (-3.5A)
None
FAD  A 501 (-3.3A)
 0.91A 4dc3B-1zr6A:
undetectable		 4dc3B-1zr6A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 LEU A  86
ALA A  39
GLY A  56
ALA A   8
VAL A  12
 None
 0.86A 4nkxB-1zr6A:
undetectable		 4nkxB-1zr6A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 GLY A 189
GLY A 187
LEU A 185
PHE A 198
GLY A 142
 None
 0.86A 4o3fA-1zr6A:
undetectable		 4o3fA-1zr6A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 5 PHE A 410
PHE A 385
LEU A 418
PRO A 324
 None
 1.36A 4o8zA-1zr6A:
undetectable		 4o8zA-1zr6A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 ARG A 422
ALA A 323
ASP A 378
LEU A 326
 None
 1.06A 4ot2A-1zr6A:
undetectable		 4ot2A-1zr6A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 SER A 243
THR A 148
SER A 362
ASP A 156
GLY A 145
 None
None
None
None
FAD  A 501 ( 4.9A)
 1.49A 4qb9E-1zr6A:
undetectable		 4qb9E-1zr6A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.47A 5b1aA-1zr6A:
0.0
5b1aB-1zr6A:
0.0
5b1aT-1zr6A:
0.0		 5b1aA-1zr6A:
21.86
5b1aB-1zr6A:
17.47
5b1aT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.47A 5b1bA-1zr6A:
0.0
5b1bB-1zr6A:
0.0
5b1bT-1zr6A:
0.0		 5b1bA-1zr6A:
21.86
5b1bB-1zr6A:
17.47
5b1bT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.47A 5b3sA-1zr6A:
0.0
5b3sB-1zr6A:
0.0
5b3sT-1zr6A:
0.0		 5b3sA-1zr6A:
21.86
5b3sB-1zr6A:
17.47
5b3sT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 TYR A 292
PRO A 131
LEU A 110
LEU A 299
 None
 1.18A 5tl8A-1zr6A:
undetectable		 5tl8A-1zr6A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UPD_A_SAMA1301_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD3)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 ARG A 377
GLY A 152
TRP A 157
TYR A 426
LEU A 382
 None
None
None
FAD  A 501 (-4.6A)
None
 1.49A 5updA-1zr6A:
undetectable		 5updA-1zr6A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 12 PHE A 260
LEU A 158
ILE A 104
ALA A 102
ALA A 205
 None
 1.03A 5vc0A-1zr6A:
undetectable		 5vc0A-1zr6A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.48A 5x19A-1zr6A:
0.6
5x19B-1zr6A:
0.0
5x19T-1zr6A:
0.0		 5x19A-1zr6A:
21.86
5x19B-1zr6A:
17.47
5x19T-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.44A 5xdqA-1zr6A:
0.0
5xdqB-1zr6A:
0.0
5xdqT-1zr6A:
0.0		 5xdqA-1zr6A:
21.86
5xdqB-1zr6A:
17.47
5xdqT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.50A 5xdxA-1zr6A:
0.3
5xdxB-1zr6A:
0.0
5xdxT-1zr6A:
0.0		 5xdxA-1zr6A:
21.86
5xdxB-1zr6A:
17.47
5xdxT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 10 ILE A 248
PHE A 334
LEU A 380
ALA A 323
LEU A 326
 None
 1.26A 5y7pB-1zr6A:
undetectable		 5y7pB-1zr6A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 10 ILE A 248
PHE A 334
LEU A 380
ALA A 323
LEU A 326
 None
 1.25A 5y7pD-1zr6A:
undetectable		 5y7pD-1zr6A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 10 ILE A 248
PHE A 334
LEU A 380
ALA A 323
LEU A 326
 None
 1.21A 5y7pH-1zr6A:
undetectable		 5y7pH-1zr6A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.45A 5z84A-1zr6A:
0.0
5z84B-1zr6A:
0.0
5z84T-1zr6A:
0.0		 5z84A-1zr6A:
21.86
5z84B-1zr6A:
17.47
5z84T-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.48A 5z86A-1zr6A:
0.6
5z86B-1zr6A:
0.0
5z86T-1zr6A:
0.0		 5z86A-1zr6A:
21.86
5z86B-1zr6A:
17.47
5z86T-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.46A 5zcoA-1zr6A:
0.0
5zcoB-1zr6A:
0.0
5zcoT-1zr6A:
0.0		 5zcoA-1zr6A:
21.86
5zcoB-1zr6A:
17.47
5zcoT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.47A 5zcpA-1zr6A:
0.0
5zcpB-1zr6A:
0.0
5zcpT-1zr6A:
0.0		 5zcpA-1zr6A:
21.86
5zcpB-1zr6A:
17.47
5zcpT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		5 / 11 GLY A  79
GLN A  62
GLU A  80
PHE A 464
GLY A 190
 None
None
None
None
FAD  A 501 (-3.4A)
 1.49A 5zcqA-1zr6A:
0.0
5zcqB-1zr6A:
0.0
5zcqT-1zr6A:
0.0		 5zcqA-1zr6A:
21.86
5zcqB-1zr6A:
17.47
5zcqT-1zr6A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 GLY A  73
THR A 432
TYR A 443
TYR A  75
 None
 1.12A 6ag0A-1zr6A:
undetectable		 6ag0A-1zr6A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 GLY A  73
THR A 432
TYR A 443
TYR A  75
 None
 1.11A 6ag0C-1zr6A:
undetectable		 6ag0C-1zr6A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 4 PRO A 272
MET A 244
GLY A 257
VAL A 214
 None
 1.41A 6ak3A-1zr6A:
undetectable		 6ak3A-1zr6A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		3 / 3 HIS A  15
ARG A  90
ILE A  42
 None
 0.69A 6fgdA-1zr6A:
undetectable		 6fgdA-1zr6A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE
(Sarocladium
strictum) 		4 / 6 LYS A 285
GLN A 213
LEU A 266
PHE A 259
 None
 1.26A 6nmpC-1zr6A:
undetectable
6nmpJ-1zr6A:
undetectable		 6nmpC-1zr6A:
18.22
6nmpJ-1zr6A:
8.53