SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zrr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1zrr E-2/E-2' PROTEIN
(Klebsiella
oxytoca) 		4 / 8 VAL A 107
GLU A 108
SER A  77
ILE A 153
 None
 0.81A 1pk7B-1zrrA:
undetectable		 1pk7B-1zrrA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QD3_A_5AEA201_1
(PEPTIDYL-TRNA
HYDROLASE)		 1zrr E-2/E-2' PROTEIN
(Klebsiella
oxytoca) 		5 / 9 LEU A 115
GLY A  32
VAL A 134
SER A 133
LEU A 131
 None
 1.20A 4qd3A-1zrrA:
undetectable		 4qd3A-1zrrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1zrr E-2/E-2' PROTEIN
(Klebsiella
oxytoca) 		3 / 3 LEU A  78
VAL A  75
ASP A  74
 None
 0.61A 4y8wC-1zrrA:
undetectable		 4y8wC-1zrrA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1zrr E-2/E-2' PROTEIN
(Klebsiella
oxytoca) 		3 / 3 ASP A 157
PHE A  92
ARG A 154
 None
None
NI  A 180 ( 4.7A)
 1.03A 5yw0A-1zrrA:
4.0		 5yw0A-1zrrA:
19.74