SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.86A 1a7yA-1zrtC:
undetectable		 1a7yA-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.83A 1a7yB-1zrtC:
undetectable		 1a7yB-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.85A 1a7yB-1zrtC:
undetectable		 1a7yB-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.84A 1dscC-1zrtC:
undetectable		 1dscC-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 VAL C 161
GLY C 164
LEU C 165
GLY C 158
PHE C 194
 SMA  C 503 (-4.4A)
None
None
SMA  C 503 (-3.3A)
SMA  C 503 (-4.7A)
 1.07A 1fduA-1zrtC:
undetectable		 1fduA-1zrtC:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 VAL C 161
GLY C 164
LEU C 165
GLY C 158
MET C 336
 SMA  C 503 (-4.4A)
None
None
SMA  C 503 (-3.3A)
SMA  C 503 (-3.3A)
 1.12A 1fduC-1zrtC:
undetectable		 1fduC-1zrtC:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.89A 1fjaC-1zrtC:
undetectable		 1fjaC-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.89A 1fjaD-1zrtC:
undetectable		 1fjaD-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 TRP C 348
VAL C 342
TRP C 129
 None
 1.39A 1gmkC-1zrtC:
undetectable
1gmkD-1zrtC:
undetectable		 1gmkC-1zrtC:
4.07
1gmkD-1zrtC:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.80A 1i3wE-1zrtC:
undetectable		 1i3wE-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.85A 1i3wF-1zrtC:
undetectable		 1i3wF-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.83A 1i3wG-1zrtC:
undetectable		 1i3wG-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.79A 1i3wG-1zrtC:
undetectable		 1i3wG-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.82A 1i3wH-1zrtC:
undetectable		 1i3wH-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.80A 1mnvD-1zrtC:
undetectable		 1mnvD-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.83A 1mnvD-1zrtC:
undetectable		 1mnvD-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 PHE C 404
ALA C 346
TYR C 136
MET C 140
ILE C 112
 None
None
None
SMA  C 503 (-4.2A)
HEM  C 502 (-3.5A)
 1.29A 1mx8A-1zrtC:
undetectable		 1mx8A-1zrtC:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		4 / 8 PHE D  11
SER D 210
ALA D 104
ILE D 131
 None
None
None
HEC  D 501 ( 4.9A)
 1.17A 1pnlA-1zrtD:
undetectable
1pnlB-1zrtD:
1.4		 1pnlA-1zrtD:
21.85
1pnlB-1zrtD:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA888_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		4 / 5 PRO D 128
MET D 214
ALA D 217
GLU D 218
 None
 1.22A 1qhsA-1zrtD:
0.0		 1qhsA-1zrtD:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		4 / 6 PRO D 128
MET D 214
ALA D 217
GLU D 218
 None
 1.50A 1qhyA-1zrtD:
undetectable		 1qhyA-1zrtD:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 LEU C 305
GLY C 338
ALA C 339
ALA C 307
ILE C 304
 SMA  C 503 ( 4.6A)
None
None
None
None
 0.86A 1rl8B-1zrtC:
undetectable		 1rl8B-1zrtC:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 SER C 155
GLY C 152
ARG C  94
 None
None
HEM  C 501 (-2.7A)
 0.67A 1t9wA-1zrtC:
undetectable		 1t9wA-1zrtC:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.78A 1unjF-1zrtC:
undetectable		 1unjF-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.86A 1unjF-1zrtC:
undetectable		 1unjF-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.83A 1unjL-1zrtC:
undetectable		 1unjL-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.85A 1unjL-1zrtC:
undetectable		 1unjL-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.82A 1unjR-1zrtC:
undetectable		 1unjR-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.83A 1unjR-1zrtC:
undetectable		 1unjR-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.84A 1unjW-1zrtC:
undetectable		 1unjW-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.82A 1unjX-1zrtC:
undetectable		 1unjX-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.84A 1unjX-1zrtC:
undetectable		 1unjX-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.82A 1unmE-1zrtC:
undetectable		 1unmE-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.85A 1unmE-1zrtC:
undetectable		 1unmE-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.85A 1unmF-1zrtC:
undetectable		 1unmF-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.82A 1unmF-1zrtC:
undetectable		 1unmF-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		3 / 3 LEU D  23
PHE D 212
ARG D  46
 None
 0.85A 1xdkB-1zrtD:
undetectable		 1xdkB-1zrtD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		3 / 3 LEU D  23
PHE D 212
ARG D  46
 None
 0.85A 1xdkF-1zrtD:
undetectable		 1xdkF-1zrtD:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 PHE C 264
ARG C  94
ASN C  99
 None
HEM  C 501 (-2.7A)
None
 0.94A 1xzxX-1zrtC:
undetectable		 1xzxX-1zrtC:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C 241
THR C  37
PRO C  36
 None
 0.88A 209dC-1zrtC:
undetectable		 209dC-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 ASP C 252
ILE C 213
VAL C  56
 None
 0.63A 2avvD-1zrtC:
undetectable		 2avvD-1zrtC:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 1zrt CYTOCHROME B
CYTOCHROME C1
(Rhodobacter
capsulatus) 		4 / 8 VAL C 293
ARG D 107
GLY D 109
ALA D 108
 None
HEC  D 501 (-3.9A)
None
None
 0.93A 2xh9A-1zrtC:
undetectable		 2xh9A-1zrtC:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1zrt UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT
(Rhodobacter
capsulatus) 		4 / 7 LEU E 190
ILE E  74
ALA E  85
ILE E  82
 None
 0.81A 2xkwA-1zrtE:
undetectable		 2xkwA-1zrtE:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		4 / 7 VAL C 186
GLY C 152
VAL C 148
ASP C 278
 None
 0.96A 2y05A-1zrtC:
undetectable
2y05B-1zrtC:
undetectable		 2y05A-1zrtC:
20.63
2y05B-1zrtC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		4 / 5 SER C 393
ARG C 306
GLY C 381
TRP C 379
 None
 0.98A 2y7kB-1zrtC:
undetectable		 2y7kB-1zrtC:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		4 / 6 SER C 393
ARG C 306
GLY C 381
TRP C 379
 None
 0.94A 2y7pA-1zrtC:
0.0		 2y7pA-1zrtC:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 ILE C 340
TRP C 129
PHE C 104
VAL C 108
PHE C 105
 None
None
HEM  C 501 ( 4.1A)
HEM  C 502 ( 4.7A)
None
 1.11A 2ygpA-1zrtC:
undetectable		 2ygpA-1zrtC:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		4 / 7 GLU D 129
ALA D 217
PRO D 128
ALA D 104
 None
 1.14A 2zgwA-1zrtD:
undetectable		 2zgwA-1zrtD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1zrt CYTOCHROME C1
(Rhodobacter
capsulatus) 		4 / 6 GLU D 129
ALA D 217
PRO D 128
ALA D 104
 None
 1.12A 2zgwB-1zrtD:
undetectable		 2zgwB-1zrtD:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.89A 316dC-1zrtC:
undetectable		 316dC-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 1zrt CYTOCHROME B
CYTOCHROME C1
(Rhodobacter
capsulatus;
Rhodobacter
capsulatus) 		5 / 12 GLN D 226
GLY C  89
VAL C  87
ALA C  92
VAL C  64
 None
 0.96A 3fpjA-1zrtD:
undetectable		 3fpjA-1zrtD:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 1zrt UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT
(Rhodobacter
capsulatus) 		3 / 3 ASP E 161
ARG E 167
ARG E  77
 None
 0.93A 3k37A-1zrtE:
undetectable		 3k37A-1zrtE:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1zrt UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT
(Rhodobacter
capsulatus) 		4 / 4 ALA E 171
HIS E 135
HIS E 156
PRO E 170
 None
FES  E 501 (-3.1A)
FES  E 501 ( 3.1A)
FES  E 501 ( 4.9A)
 1.42A 3mbgA-1zrtE:
undetectable		 3mbgA-1zrtE:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1zrt CYTOCHROME B
CYTOCHROME C1
(Rhodobacter
capsulatus) 		5 / 12 ASP C 278
ILE D 131
GLY D 126
ALA D 106
ALA D 104
 None
HEC  D 501 ( 4.9A)
None
None
None
 0.99A 3sudC-1zrtC:
undetectable		 3sudC-1zrtC:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1zrt CYTOCHROME B
CYTOCHROME C1
(Rhodobacter
capsulatus) 		5 / 12 ASP C 278
ILE D 131
GLY D 126
ALA D 106
ALA D 104
 None
HEC  D 501 ( 4.9A)
None
None
None
 0.97A 3sufD-1zrtC:
undetectable		 3sufD-1zrtC:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 10 PHE C 104
VAL C 108
PHE C 105
ILE C 135
GLY C 132
 HEM  C 501 ( 4.1A)
HEM  C 502 ( 4.7A)
None
HEM  C 502 (-3.8A)
HEM  C 502 (-3.6A)
 1.27A 3t3rD-1zrtC:
undetectable		 3t3rD-1zrtC:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 ARG C 355
LYS C 122
ARG C 360
 None
 1.03A 3w1wA-1zrtC:
0.0
3w1wB-1zrtC:
0.0		 3w1wA-1zrtC:
20.52
3w1wB-1zrtC:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 THR C  37
PRO C  36
THR C 241
 None
 0.75A 4hivD-1zrtC:
undetectable		 4hivD-1zrtC:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 ASP C 373
TYR C 399
TRP C 400
 None
 1.34A 4p7nA-1zrtC:
undetectable		 4p7nA-1zrtC:
21.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		8 / 12 GLY C 158
ILE C 162
ILE C 292
PRO C 294
PHE C 301
TYR C 302
LEU C 305
ILE C 340
 SMA  C 503 (-3.3A)
None
SMA  C 503 ( 4.5A)
SMA  C 503 (-4.1A)
SMA  C 503 (-4.7A)
SMA  C 503 (-4.2A)
SMA  C 503 ( 4.6A)
None
 0.93A 4pd4C-1zrtC:
48.6		 4pd4C-1zrtC:
44.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		8 / 12 GLY C 158
ILE C 162
PRO C 294
PHE C 301
TYR C 302
LEU C 305
MET C 336
ILE C 340
 SMA  C 503 (-3.3A)
None
SMA  C 503 (-4.1A)
SMA  C 503 (-4.7A)
SMA  C 503 (-4.2A)
SMA  C 503 ( 4.6A)
SMA  C 503 (-3.3A)
None
 0.88A 4pd4C-1zrtC:
48.6		 4pd4C-1zrtC:
44.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		8 / 12 GLY C 158
VAL C 161
ILE C 162
ILE C 292
PHE C 301
TYR C 302
LEU C 305
ILE C 340
 SMA  C 503 (-3.3A)
SMA  C 503 (-4.4A)
None
SMA  C 503 ( 4.5A)
SMA  C 503 (-4.7A)
SMA  C 503 (-4.2A)
SMA  C 503 ( 4.6A)
None
 0.86A 4pd4C-1zrtC:
48.6		 4pd4C-1zrtC:
44.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		8 / 12 GLY C 158
VAL C 161
ILE C 162
PHE C 301
TYR C 302
LEU C 305
MET C 336
ILE C 340
 SMA  C 503 (-3.3A)
SMA  C 503 (-4.4A)
None
SMA  C 503 (-4.7A)
SMA  C 503 (-4.2A)
SMA  C 503 ( 4.6A)
SMA  C 503 (-3.3A)
None
 0.82A 4pd4C-1zrtC:
48.6		 4pd4C-1zrtC:
44.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 GLY C 115
TYR C 117
ILE C 112
ILE C 110
HIS C 111
 None
None
HEM  C 502 (-3.5A)
None
HEM  C 502 (-3.1A)
 1.37A 4xucA-1zrtC:
undetectable		 4xucA-1zrtC:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 GLY C 115
TYR C 117
ILE C 112
ILE C 110
HIS C 111
 None
None
HEM  C 502 (-3.5A)
None
HEM  C 502 (-3.1A)
 1.39A 4xudA-1zrtC:
undetectable		 4xudA-1zrtC:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZF_E_AZ1E2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
6J9-ZEU-DAR-ACA-DAR-
NH2)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		4 / 7 GLY C 158
PHE C 166
LEU C 180
GLU C 295
 SMA  C 503 (-3.3A)
SMA  C 503 (-4.2A)
SMA  C 503 (-4.1A)
SMA  C 503 (-3.7A)
 0.85A 5izfA-1zrtC:
undetectable		 5izfA-1zrtC:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		4 / 6 HIS C 291
VAL C 293
TYR C 302
ARG C 306
 None
None
SMA  C 503 (-4.2A)
None
 0.90A 5kkzA-1zrtC:
51.3
5kkzG-1zrtC:
undetectable		 5kkzA-1zrtC:
82.47
5kkzG-1zrtC:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 7 HIS C 291
ILE C 292
VAL C 293
TYR C 302
ARG C 306
 None
SMA  C 503 ( 4.5A)
None
SMA  C 503 (-4.2A)
None
 0.91A 5kkzC-1zrtC:
undetectable
5kkzE-1zrtC:
51.1		 5kkzC-1zrtC:
15.63
5kkzE-1zrtC:
82.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 7 HIS C 291
ILE C 292
VAL C 293
TYR C 302
ARG C 306
 None
SMA  C 503 ( 4.5A)
None
SMA  C 503 (-4.2A)
None
 0.93A 5kkzK-1zrtC:
54.3
5kkzQ-1zrtC:
undetectable		 5kkzK-1zrtC:
82.47
5kkzQ-1zrtC:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 7 HIS C 291
ILE C 292
VAL C 293
TYR C 302
ARG C 306
 None
SMA  C 503 ( 4.5A)
None
SMA  C 503 (-4.2A)
None
 0.85A 5kkzM-1zrtC:
undetectable
5kkzO-1zrtC:
51.3		 5kkzM-1zrtC:
15.63
5kkzO-1zrtC:
82.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 PHE C 369
ASP C 373
LEU C 349
 None
 0.70A 5uhbC-1zrtC:
undetectable		 5uhbC-1zrtC:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHC_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 PHE C 369
ASP C 373
LEU C 349
 None
 0.71A 5uhcC-1zrtC:
undetectable		 5uhcC-1zrtC:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		5 / 12 GLY C 119
PHE C 404
PHE C 367
PHE C 363
VAL C 371
 None
 1.41A 6a94A-1zrtC:
undetectable		 6a94A-1zrtC:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 1zrt CYTOCHROME B
(Rhodobacter
capsulatus) 		3 / 3 TYR C 403
ALA C 346
LEU C 116
 None
 0.76A 6d9kF-1zrtC:
undetectable		 6d9kF-1zrtC:
19.90