SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zs8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 1zs8 HISTOCOMPATIBILITY
2, M REGION LOCUS
10.5
(Mus
musculus) 		4 / 8 LEU A 271
LYS A 242
ALA A 204
THR A 186
 None
 0.92A 1ie4B-1zs8A:
undetectable
1ie4D-1zs8A:
undetectable		 1ie4B-1zs8A:
18.68
1ie4D-1zs8A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 1zs8 HISTOCOMPATIBILITY
2, M REGION LOCUS
10.5
(Mus
musculus) 		3 / 3 ARG A   8
GLU A  62
TYR A  32
 None
 0.90A 3k37B-1zs8A:
undetectable		 3k37B-1zs8A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1zs8 HISTOCOMPATIBILITY
2, M REGION LOCUS
10.5
(Mus
musculus) 		4 / 4 LEU A 265
ILE A 212
HIS A 262
VAL A 260
 None
 1.28A 4xyzA-1zs8A:
undetectable		 4xyzA-1zs8A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1zs8 HISTOCOMPATIBILITY
2, M REGION LOCUS
10.5
(Mus
musculus) 		4 / 6 TYR A 117
ASP A  90
HIS A  92
ILE A  11
 None
 1.20A 5ih0A-1zs8A:
undetectable		 5ih0A-1zs8A:
23.05