SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 11 LEU A 151
LEU A  12
ALA A  10
ASN A  89
VAL A 117
 None
 1.29A 3e22B-1zsoA:
undetectable		 3e22B-1zsoA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 11 LEU A 151
LEU A  12
ALA A  10
ASN A  89
VAL A 117
 None
 1.30A 3e22D-1zsoA:
undetectable		 3e22D-1zsoA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 12 TRP A  26
PHE A  44
ILE A  74
VAL A   6
VAL A 155
 None
 1.21A 4yfbC-1zsoA:
0.0		 4yfbC-1zsoA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 12 TRP A  26
PHE A  44
ILE A  74
VAL A   6
VAL A 155
 None
 1.21A 4yfbF-1zsoA:
0.0		 4yfbF-1zsoA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 12 TRP A  26
PHE A  44
ILE A  74
VAL A   6
VAL A 155
 None
 1.20A 4yfbI-1zsoA:
undetectable		 4yfbI-1zsoA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 12 TRP A  26
PHE A  44
ILE A  74
VAL A   6
VAL A 155
 None
 1.19A 4yfbL-1zsoA:
undetectable		 4yfbL-1zsoA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUO_D_PFLD402_1
(PROTON-GATED ION
CHANNEL)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		5 / 9 THR A  34
SER A  33
SER A  72
ILE A 104
THR A  66
 None
 1.44A 5muoA-1zsoA:
undetectable
5muoB-1zsoA:
0.0
5muoC-1zsoA:
0.0
5muoD-1zsoA:
undetectable
5muoE-1zsoA:
0.0		 5muoA-1zsoA:
16.67
5muoB-1zsoA:
16.67
5muoC-1zsoA:
16.67
5muoD-1zsoA:
16.67
5muoE-1zsoA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1zso HYPOTHETICAL PROTEIN
(Plasmodium
falciparum) 		4 / 5 ARG A  45
TYR A  24
GLN A  43
ILE A  27
 None
 1.36A 6g9bA-1zsoA:
undetectable
6g9bB-1zsoA:
undetectable		 6g9bA-1zsoA:
19.51
6g9bB-1zsoA:
12.80