SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zsq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.76A 1c9sI-1zsqA:
undetectable
1c9sJ-1zsqA:
undetectable		 1c9sI-1zsqA:
12.02
1c9sJ-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.73A 1c9sT-1zsqA:
undetectable
1c9sU-1zsqA:
undetectable		 1c9sT-1zsqA:
12.02
1c9sU-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.72A 1c9sU-1zsqA:
undetectable
1c9sV-1zsqA:
undetectable		 1c9sU-1zsqA:
12.02
1c9sV-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 ASP A 510
ASP A 157
TYR A 110
ARG A 111
 None
 1.17A 1ceaA-1zsqA:
undetectable
1ceaB-1zsqA:
undetectable		 1ceaA-1zsqA:
8.80
1ceaB-1zsqA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASP A 510
ASP A 157
TYR A 110
ARG A 111
 None
 1.13A 1ceaB-1zsqA:
undetectable		 1ceaB-1zsqA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASP A 510
ASP A 157
TYR A 110
ARG A 111
 None
 1.18A 1cebA-1zsqA:
undetectable		 1cebA-1zsqA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASP A 510
ASP A 157
TYR A 110
ARG A 111
 None
 1.14A 1cebB-1zsqA:
undetectable		 1cebB-1zsqA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 PHE A 483
ILE A 484
PHE A 520
VAL A 487
 None
 0.87A 1fslA-1zsqA:
undetectable		 1fslA-1zsqA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 4 VAL A 577
TRP A 388
TRP A 488
 None
 1.45A 1gmkC-1zsqA:
undetectable
1gmkD-1zsqA:
undetectable		 1gmkC-1zsqA:
3.08
1gmkD-1zsqA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.74A 1gtfL-1zsqA:
undetectable
1gtfM-1zsqA:
undetectable		 1gtfL-1zsqA:
12.02
1gtfM-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.72A 1gtfN-1zsqA:
undetectable
1gtfO-1zsqA:
undetectable		 1gtfN-1zsqA:
12.02
1gtfO-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.72A 1gtnA-1zsqA:
undetectable
1gtnK-1zsqA:
undetectable		 1gtnA-1zsqA:
12.02
1gtnK-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.74A 1gtnA-1zsqA:
undetectable
1gtnB-1zsqA:
undetectable		 1gtnA-1zsqA:
12.02
1gtnB-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.78A 1gtnC-1zsqA:
undetectable
1gtnD-1zsqA:
undetectable		 1gtnC-1zsqA:
12.02
1gtnD-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.75A 1gtnD-1zsqA:
undetectable
1gtnE-1zsqA:
undetectable		 1gtnD-1zsqA:
12.02
1gtnE-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 1gtnE-1zsqA:
undetectable
1gtnF-1zsqA:
undetectable		 1gtnE-1zsqA:
12.02
1gtnF-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.75A 1gtnF-1zsqA:
undetectable
1gtnG-1zsqA:
undetectable		 1gtnF-1zsqA:
12.02
1gtnG-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.73A 1gtnI-1zsqA:
undetectable
1gtnJ-1zsqA:
undetectable		 1gtnI-1zsqA:
12.02
1gtnJ-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.74A 1gtnJ-1zsqA:
undetectable
1gtnK-1zsqA:
undetectable		 1gtnJ-1zsqA:
12.02
1gtnK-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.71A 1gtnP-1zsqA:
undetectable
1gtnQ-1zsqA:
undetectable		 1gtnP-1zsqA:
12.02
1gtnQ-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I6V_C_RFPC1640_1
(DNA-DIRECTED RNA
POLYMERASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 ARG A 459
HIS A 458
ARG A 463
SER A 477
ILE A 356
 PIB  A3632 ( 4.8A)
EDO  A1878 (-3.9A)
PIB  A3632 ( 3.8A)
None
PIB  A3632 (-3.9A)
 1.30A 1i6vC-1zsqA:
0.2		 1i6vC-1zsqA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N3Z_A_ADNA126_1
(RIBONUCLEASE,
SEMINAL)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 9 GLN A 312
ASN A 310
ALA A 279
VAL A 406
HIS A 274
 None
 1.43A 1n3zA-1zsqA:
undetectable		 1n3zA-1zsqA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.77A 1utdB-1zsqA:
undetectable
1utdC-1zsqA:
undetectable		 1utdB-1zsqA:
12.02
1utdC-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.76A 1utdF-1zsqA:
undetectable
1utdG-1zsqA:
undetectable		 1utdF-1zsqA:
12.02
1utdG-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.77A 1utdI-1zsqA:
undetectable
1utdJ-1zsqA:
undetectable		 1utdI-1zsqA:
12.02
1utdJ-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PIB  A3632 (-3.7A)
None
None
None
 0.75A 1utdJ-1zsqA:
undetectable
1utdK-1zsqA:
undetectable		 1utdJ-1zsqA:
12.02
1utdK-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 5 TYR A 371
ILE A  94
TYR A  93
THR A  92
 None
 1.45A 3dgqA-1zsqA:
undetectable		 3dgqA-1zsqA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 9 LEU A 348
VAL A 414
ILE A 306
PRO A 287
ILE A 318
 None
 1.12A 3ekqB-1zsqA:
undetectable		 3ekqB-1zsqA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 CYH A 284
THR A 282
LEU A 303
ILE A 316
LEU A 244
 None
 1.42A 3gwxB-1zsqA:
undetectable		 3gwxB-1zsqA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 SER A 418
ASP A 320
ASP A 422
 PIB  A3632 (-2.5A)
None
PIB  A3632 (-3.6A)
 0.88A 3iv6A-1zsqA:
undetectable		 3iv6A-1zsqA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 SER A 418
ASP A 320
ASP A 422
 PIB  A3632 (-2.5A)
None
PIB  A3632 (-3.6A)
 0.92A 3iv6C-1zsqA:
undetectable		 3iv6C-1zsqA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 ALA A 472
ARG A 476
LYS A 156
 EDO  A1879 (-4.4A)
None
None
 1.02A 3kp3B-1zsqA:
0.0		 3kp3B-1zsqA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 TYR A 209
ILE A 544
PHE A 500
PHE A 551
ILE A 508
 None
 1.31A 3ndiA-1zsqA:
undetectable		 3ndiA-1zsqA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 GLU A 300
TYR A 343
SER A 339
 None
 0.98A 4at0A-1zsqA:
undetectable		 4at0A-1zsqA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 ALA A 431
ILE A 353
GLY A 398
ILE A 281
 None
 0.74A 4r21A-1zsqA:
undetectable		 4r21A-1zsqA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		6 / 12 LEU A 433
VAL A 487
LEU A 540
ILE A 508
LEU A 505
VAL A 449
 None
 1.44A 4y0qA-1zsqA:
undetectable		 4y0qA-1zsqA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 5eevL-1zsqA:
undetectable
5eevV-1zsqA:
undetectable		 5eevL-1zsqA:
12.02
5eevV-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 5eewL-1zsqA:
undetectable
5eewV-1zsqA:
undetectable		 5eewL-1zsqA:
12.02
5eewV-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 5eezL-1zsqA:
undetectable
5eezV-1zsqA:
undetectable		 5eezL-1zsqA:
12.02
5eezV-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 5ef1L-1zsqA:
undetectable
5ef1V-1zsqA:
undetectable		 5ef1L-1zsqA:
12.02
5ef1V-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 5ef2L-1zsqA:
undetectable
5ef2V-1zsqA:
undetectable		 5ef2L-1zsqA:
12.02
5ef2V-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PIB  A3632 (-3.7A)
None
None
 0.71A 5ef3L-1zsqA:
undetectable
5ef3V-1zsqA:
undetectable		 5ef3L-1zsqA:
12.02
5ef3V-1zsqA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 TYR A 439
TYR A 215
GLN A 218
 None
 0.95A 5jsdA-1zsqA:
undetectable
5jsdB-1zsqA:
undetectable		 5jsdA-1zsqA:
21.36
5jsdB-1zsqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 TYR A 439
TYR A 215
GLN A 218
 None
 0.95A 5jsdB-1zsqA:
undetectable
5jsdC-1zsqA:
undetectable		 5jsdB-1zsqA:
21.36
5jsdC-1zsqA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 ASN A 523
ARG A 528
GLN A 526
GLY A 529
 None
 0.98A 5nzyA-1zsqA:
undetectable		 5nzyA-1zsqA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		6 / 11 LEU A 433
GLY A 437
SER A 429
VAL A 447
THR A 441
GLU A 499
 None
 1.16A 5o96G-1zsqA:
undetectable		 5o96G-1zsqA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 LEU A 430
ILE A 353
ALA A 568
LEU A 573
 None
 0.86A 5y7pC-1zsqA:
undetectable		 5y7pC-1zsqA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 ILE A 544
SER A 539
LEU A 505
PHE A 445
PHE A 480
 None
 1.42A 6dwnB-1zsqA:
undetectable		 6dwnB-1zsqA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 ASN A 545
LEU A 540
SER A 539
PHE A 520
 None
 1.13A 6ekuA-1zsqA:
undetectable		 6ekuA-1zsqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 1zsq MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 TRP A 488
ILE A 484
ASP A 485
 None
 0.90A 6i0y7-1zsqA:
undetectable		 6i0y7-1zsqA:
4.09