SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ztm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		4 / 7 GLY A 215
THR A 211
TYR A 207
ASP A 216
 None
 1.07A 2g70B-1ztmA:
undetectable		 2g70B-1ztmA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 8 LEU A  53
ILE A  79
LEU A  78
THR A 211
LEU A 210
 None
 1.23A 2xfhA-1ztmA:
undetectable		 2xfhA-1ztmA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 10 LEU A 323
ILE A 316
GLY A 325
GLY A 345
THR A 291
 None
 0.98A 4fakA-1ztmA:
undetectable		 4fakA-1ztmA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		4 / 7 CSS A 340
ILE A  40
PRO A 344
ILE A 293
 None
 0.98A 4z4gA-1ztmA:
undetectable		 4z4gA-1ztmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		4 / 6 ILE A 411
ALA A 377
VAL A 379
VAL A 409
 None
 0.90A 5eclD-1ztmA:
undetectable		 5eclD-1ztmA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		4 / 8 THR A 390
SER A 300
ALA A 377
ASP A 297
 None
 1.13A 5l5fY-1ztmA:
undetectable
5l5fZ-1ztmA:
undetectable		 5l5fY-1ztmA:
15.65
5l5fZ-1ztmA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 GLY A 225
VAL A 269
LEU A  86
GLY A 219
ILE A 218
 None
 1.12A 5vooA-1ztmA:
undetectable		 5vooA-1ztmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 GLY A 225
VAL A 269
LEU A  86
GLY A 219
ILE A 218
 None
 1.10A 5vooB-1ztmA:
undetectable		 5vooB-1ztmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 GLY A 225
VAL A 269
LEU A  86
GLY A 219
ILE A 218
 None
 1.12A 5vooC-1ztmA:
undetectable		 5vooC-1ztmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 GLY A 225
VAL A 269
LEU A  86
GLY A 219
ILE A 218
 None
 1.17A 5vooD-1ztmA:
undetectable		 5vooD-1ztmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 GLY A 225
VAL A 269
LEU A  86
GLY A 219
ILE A 218
 None
 1.19A 5vooE-1ztmA:
undetectable		 5vooE-1ztmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 GLY A 225
VAL A 269
LEU A  86
GLY A 219
ILE A 218
 None
 1.18A 5vooF-1ztmA:
undetectable		 5vooF-1ztmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		5 / 12 HIS A 206
SER A  52
SER A 275
PHE A 214
LEU A 203
 None
 1.30A 6chgC-1ztmA:
undetectable		 6chgC-1ztmA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 1ztm FUSION GLYCOPROTEIN
(Human
respirovirus
3) 		3 / 3 LEU A  49
ASP A 270
ILE A  79
 None
 0.62A 6dh0B-1ztmA:
undetectable		 6dh0B-1ztmA:
11.23