SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ztv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		3 / 3 SER A  81
GLU A  82
GLU A  83
 None
 0.56A 1eqbD-1ztvA:
undetectable		 1eqbD-1ztvA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		3 / 3 SER A  81
GLU A  82
GLU A  83
 None
 0.57A 1eqbB-1ztvA:
undetectable		 1eqbB-1ztvA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 8 VAL A 167
VAL A 165
SER A 163
ILE A 135
 None
 0.89A 1igxA-1ztvA:
undetectable		 1igxA-1ztvA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 8 SER A  99
LEU A 133
PHE A 105
PHE A  89
MET A  93
 None
 1.40A 1wrlC-1ztvA:
undetectable
1wrlD-1ztvA:
undetectable		 1wrlC-1ztvA:
16.03
1wrlD-1ztvA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A   4
PHE A 243
LEU A 262
ALA A 223
ILE A 222
 None
 0.83A 2bxpA-1ztvA:
undetectable		 2bxpA-1ztvA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 6 SER A  92
TYR A  78
SER A  70
GLN A  72
 None
 1.28A 2cl5B-1ztvA:
undetectable		 2cl5B-1ztvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		3 / 3 GLY A  17
ASP A  13
SER A  21
 None
 0.67A 2qhfA-1ztvA:
undetectable		 2qhfA-1ztvA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3V_A_TOPA1169_1
(DIHYDROFOLATE
REDUCTASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 12 VAL A 107
LEU A 133
PHE A 130
SER A  92
ILE A  69
 None
 1.12A 2w3vA-1ztvA:
undetectable		 2w3vA-1ztvA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 10 LEU A 133
ALA A 104
SER A  70
ILE A  69
PHE A 130
 None
 1.04A 2w9gA-1ztvA:
undetectable		 2w9gA-1ztvA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 6 SER A  92
TYR A  78
SER A  70
GLN A  72
 None
 1.25A 2zvjA-1ztvA:
undetectable		 2zvjA-1ztvA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 12 ASN A 218
PHE A 193
GLY A 195
TYR A 215
PHE A 191
 None
 1.22A 3a27A-1ztvA:
undetectable		 3a27A-1ztvA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 12 PRO A 134
LEU A 102
ASN A 185
THR A   7
LEU A  32
 None
 1.46A 3a51B-1ztvA:
undetectable		 3a51B-1ztvA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 11 LEU A 133
ALA A 104
SER A  70
ILE A  69
PHE A 130
 None
 1.05A 3frbX-1ztvA:
undetectable		 3frbX-1ztvA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 5 ASN A 244
THR A  37
SER A   8
SER A  10
 None
 1.43A 3hlwB-1ztvA:
undetectable		 3hlwB-1ztvA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 7 VAL A 167
VAL A 165
LEU A 164
SER A 163
 None
 0.64A 3hs6B-1ztvA:
undetectable		 3hs6B-1ztvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		3 / 3 VAL A  62
VAL A 165
SER A 163
 None
 0.66A 3n8xB-1ztvA:
undetectable		 3n8xB-1ztvA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 8 ASN A 254
ALA A 252
LEU A  30
LEU A   6
 None
 0.98A 4jjkA-1ztvA:
undetectable		 4jjkA-1ztvA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 5 PHE A 191
ASP A 168
PHE A 193
VAL A 229
 None
 1.11A 5a1rA-1ztvA:
undetectable		 5a1rA-1ztvA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A  86
ALA A  88
ILE A  97
LEU A 133
PRO A 134
 None
 1.09A 5eajB-1ztvA:
undetectable		 5eajB-1ztvA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		5 / 11 TYR A  39
THR A  37
LEU A 106
PRO A  43
ILE A  42
 None
 1.36A 5ewjA-1ztvA:
undetectable
5ewjB-1ztvA:
undetectable		 5ewjA-1ztvA:
21.21
5ewjB-1ztvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 4 ASN A 187
ILE A 166
TYR A 182
PHE A 156
 None
 1.30A 5igvA-1ztvA:
undetectable		 5igvA-1ztvA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 6 VAL A  62
VAL A 165
SER A 163
ARG A 127
 None
 0.90A 5jw1B-1ztvA:
undetectable		 5jw1B-1ztvA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		3 / 3 VAL A 150
TYR A 145
GLN A 146
 None
 0.74A 5qgkA-1ztvA:
undetectable		 5qgkA-1ztvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		3 / 3 VAL A 150
TYR A 145
GLN A 146
 None
 0.71A 5qgrA-1ztvA:
undetectable		 5qgrA-1ztvA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 1ztv HYPOTHETICAL PROTEIN
(Enterococcus
faecalis) 		4 / 7 ARG A 212
TRP A 201
THR A 174
PRO A 176
 CL  A 278 ( 4.6A)
None
None
None
 1.34A 6a4iB-1ztvA:
undetectable		 6a4iB-1ztvA:
23.48