SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zub'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 VAL A 699
VAL A 614
TRP A 673
 None
 0.98A 1av2A-1zubA:
undetectable
1av2B-1zubA:
undetectable		 1av2A-1zubA:
8.41
1av2B-1zubA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		3 / 3 VAL A 699
VAL A 614
TRP A 673
 None
 0.99A 1w5uA-1zubA:
undetectable
1w5uB-1zubA:
undetectable		 1w5uA-1zubA:
8.41
1w5uB-1zubA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 LEU A 645
VAL A 614
LEU A 616
ARG A 665
 None
 1.06A 2oiqA-1zubA:
undetectable		 2oiqA-1zubA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		5 / 12 ILE A 702
GLY A 675
SER A 693
LEU A 630
ILE A 615
 None
 1.15A 3adsB-1zubA:
undetectable		 3adsB-1zubA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		4 / 7 GLY A 662
VAL A 670
ILE A 702
VAL A 703
 None
 0.57A 5ik1A-1zubA:
undetectable		 5ik1A-1zubA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		4 / 5 ILE A 702
LEU A 632
HIS A 663
VAL A 599
 None
 1.12A 5jmnB-1zubA:
undetectable		 5jmnB-1zubA:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		5 / 7 GLY A 662
LEU A 664
GLY A 631
LEU A 630
ILE A 689
 None
 1.12A 5vkqA-1zubA:
undetectable
5vkqB-1zubA:
undetectable		 5vkqA-1zubA:
5.46
5vkqB-1zubA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		5 / 8 GLY A 662
LEU A 664
GLY A 631
LEU A 630
ILE A 689
 None
 1.12A 5vkqB-1zubA:
undetectable
5vkqC-1zubA:
undetectable		 5vkqB-1zubA:
5.46
5vkqC-1zubA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1zub REGULATING SYNAPTIC
MEMBRANE EXOCYTOSIS
PROTEIN 1
(Rattus
norvegicus) 		5 / 8 GLY A 662
LEU A 664
VAL A 670
GLY A 631
LEU A 630
 None
 1.08A 5vkqB-1zubA:
undetectable
5vkqC-1zubA:
undetectable		 5vkqB-1zubA:
5.46
5vkqC-1zubA:
5.46