SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		5 / 12 LEU 1 107
GLY 1  40
GLY 1  37
ILE 1  34
THR 1  54
 None
 1.10A 1p91B-1zud1:
3.8		 1p91B-1zud1:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		5 / 9 LEU 1 221
GLY 1 155
GLY 1 224
SER 1 231
LEU 1 158
 None
 1.08A 2qmmA-1zud1:
3.3		 2qmmA-1zud1:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		4 / 6 LEU 1  36
ALA 1  43
LEU 1  45
ALA 1  48
 None
 0.92A 2vcvK-1zud1:
undetectable		 2vcvK-1zud1:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		5 / 12 GLY 1  40
GLY 1  37
THR 1  41
LEU 1  73
ILE 1  33
 None
 1.00A 2wa2B-1zud1:
4.8		 2wa2B-1zud1:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		3 / 3 LEU 1  15
ARG 1  11
ILE 1  18
 None
 0.59A 2xn5B-1zud1:
undetectable		 2xn5B-1zud1:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		4 / 5 LEU 1 100
GLN 1  93
THR 1  92
LEU 1  36
 None
 1.18A 3ce6D-1zud1:
6.0		 3ce6D-1zud1:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		5 / 9 ALA 1  44
GLY 1  40
LEU 1 123
LEU 1  39
ILE 1 147
 None
 1.44A 3wdmA-1zud1:
undetectable		 3wdmA-1zud1:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		5 / 12 ARG 1 132
GLY 1  38
GLY 1  37
GLY 1  40
VAL 1 194
 None
 0.98A 4htfA-1zud1:
5.4		 4htfA-1zud1:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		5 / 12 ARG 1 132
GLY 1  38
GLY 1  37
GLY 1  40
VAL 1 194
 None
 0.98A 4htfB-1zud1:
5.4		 4htfB-1zud1:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1zud ADENYLYLTRANSFERASE
THIF
(Escherichia
coli) 		4 / 8 ALA 1  43
LEU 1  73
LEU 1  55
LEU 1  91
 None
 0.69A 5jqbA-1zud1:
undetectable
5jqbB-1zud1:
undetectable		 5jqbA-1zud1:
19.94
5jqbB-1zud1:
19.05