SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zuj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1zuj HYPOTHETICAL PROTEIN
LLACC01001955
(Lactococcus
lactis) 		5 / 10 ALA A  27
LEU A 144
GLU A  84
LEU A  79
THR A  26
 None
 1.15A 3fl9E-1zujA:
undetectable		 3fl9E-1zujA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 1zuj HYPOTHETICAL PROTEIN
LLACC01001955
(Lactococcus
lactis) 		3 / 3 TYR A  57
TYR A 161
GLU A 112
 None
 0.75A 3pfgA-1zujA:
undetectable		 3pfgA-1zujA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1zuj HYPOTHETICAL PROTEIN
LLACC01001955
(Lactococcus
lactis) 		5 / 12 ALA A 147
LYS A 150
LEU A 151
LYS A  67
ILE A  38
 None
 1.10A 3ut5B-1zujA:
undetectable		 3ut5B-1zujA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1zuj HYPOTHETICAL PROTEIN
LLACC01001955
(Lactococcus
lactis) 		5 / 12 ALA A 147
LYS A 150
LEU A 151
LYS A  67
ILE A  38
 None
 1.11A 3ut5D-1zujA:
undetectable		 3ut5D-1zujA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 1zuj HYPOTHETICAL PROTEIN
LLACC01001955
(Lactococcus
lactis) 		3 / 3 PRO A  87
ASN A  96
HIS A  22
 None
 1.03A 4ma3H-1zujA:
undetectable
4ma3L-1zujA:
undetectable		 4ma3H-1zujA:
21.74
4ma3L-1zujA:
18.45