SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zuo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		4 / 7 PHE A 272
LEU A 209
ALA A 205
PHE A 278
 None
 0.84A 1epbA-1zuoA:
undetectable		 1epbA-1zuoA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		4 / 7 LEU A 236
SER A 235
ASP A 238
PHE A 278
 None
 1.17A 1ismB-1zuoA:
undetectable		 1ismB-1zuoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		4 / 8 PHE A 274
VAL A 322
VAL A 229
VAL A 241
 None
 0.75A 1iwiA-1zuoA:
undetectable		 1iwiA-1zuoA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		3 / 3 ASP A 215
ARG A 218
ARG A 214
 None
 1.07A 2j9dA-1zuoA:
undetectable
2j9dC-1zuoA:
undetectable		 2j9dA-1zuoA:
18.82
2j9dC-1zuoA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		5 / 11 SER A 228
LEU A 303
LEU A 330
LEU A 243
LEU A 292
 None
 0.99A 2xn5A-1zuoA:
undetectable		 2xn5A-1zuoA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		4 / 8 PHE A 274
VAL A 322
VAL A 229
VAL A 241
 None
 0.84A 2zujA-1zuoA:
undetectable		 2zujA-1zuoA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		5 / 10 SER A 228
LEU A 303
LEU A 330
LEU A 243
LEU A 292
 None
 0.96A 4yiaA-1zuoA:
undetectable		 4yiaA-1zuoA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		4 / 4 TYR A 346
GLY A 294
SER A 293
LEU A 292
 None
 1.39A 5bphC-1zuoA:
undetectable		 5bphC-1zuoA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1zuo HYPOTHETICAL PROTEIN
LOC92912
(Homo
sapiens) 		4 / 6 ASP A 281
ASP A 238
ASN A 271
GLN A 352
 None
 1.24A 5l6eA-1zuoA:
undetectable		 5l6eA-1zuoA:
18.97