SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zuw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.02A 1c9sP-1zuwA:
undetectable
1c9sQ-1zuwA:
undetectable
1c9sP-1zuwA:
13.97
1c9sQ-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 1gtfJ-1zuwA:
undetectable
1gtfK-1zuwA:
undetectable
1gtfJ-1zuwA:
13.97
1gtfK-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.01A 1gtfQ-1zuwA:
undetectable
1gtfR-1zuwA:
undetectable
1gtfQ-1zuwA:
13.97
1gtfR-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.03A 1gtfS-1zuwA:
undetectable
1gtfT-1zuwA:
undetectable
1gtfS-1zuwA:
13.97
1gtfT-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.05A 1gtnT-1zuwA:
undetectable
1gtnU-1zuwA:
undetectable
1gtnT-1zuwA:
13.97
1gtnU-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 6 TYR A 188
VAL A  96
ILE A  97
LEU A 181
None
1.08A 1j96A-1zuwA:
undetectable
1j96A-1zuwA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 7 TYR A 188
VAL A  96
ILE A  97
LEU A 181
None
1.09A 1j96B-1zuwA:
undetectable
1j96B-1zuwA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 SER A 208
LEU A 148
LEU A 143
LEU A 173
MET A 199
None
1.19A 1p33A-1zuwA:
3.5
1p33A-1zuwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 SER A 208
LEU A 148
LEU A 143
LEU A 173
MET A 199
None
1.15A 1p33B-1zuwA:
2.9
1p33B-1zuwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 SER A 208
LEU A 148
LEU A 143
LEU A 173
MET A 199
None
1.08A 1p33C-1zuwA:
3.6
1p33C-1zuwA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 8 ALA A  19
LEU A  16
GLY A  14
GLY A  35
None
0.77A 1rukH-1zuwA:
undetectable
1rukL-1zuwA:
undetectable
1rukH-1zuwA:
22.57
1rukL-1zuwA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 GLY A 117
THR A 186
VAL A 149
GLU A 153
PRO A  44
None
DGL  A1301 (-3.1A)
None
None
None
1.25A 1sg9A-1zuwA:
2.3
1sg9A-1zuwA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.06A 1utdE-1zuwA:
undetectable
1utdF-1zuwA:
undetectable
1utdE-1zuwA:
13.97
1utdF-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.06A 1utdH-1zuwA:
undetectable
1utdI-1zuwA:
undetectable
1utdH-1zuwA:
13.97
1utdI-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 HIS A 187
THR A 121
THR A 118
GLY A 184
THR A 186
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
None
DGL  A1301 (-3.1A)
1.03A 1utdS-1zuwA:
undetectable
1utdT-1zuwA:
undetectable
1utdS-1zuwA:
13.97
1utdT-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.05A 1utdL-1zuwA:
undetectable
1utdV-1zuwA:
undetectable
1utdL-1zuwA:
13.97
1utdV-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 8 SER A 208
LEU A 148
LEU A 143
LEU A 173
None
0.93A 2bfpC-1zuwA:
3.2
2bfpC-1zuwA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 8 ALA A  81
THR A  58
ILE A   9
THR A  54
None
0.94A 3bpxA-1zuwA:
undetectable
3bpxB-1zuwA:
undetectable
3bpxA-1zuwA:
19.12
3bpxB-1zuwA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 9 ILE A 178
ILE A 113
VAL A 203
ILE A 206
ILE A 205
None
1.26A 3p4wB-1zuwA:
undetectable
3p4wB-1zuwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 VAL A  96
ASN A  75
ALA A  77
THR A  54
ILE A   9
None
DGL  A1301 (-4.1A)
None
None
None
1.37A 3t3qD-1zuwA:
undetectable
3t3qD-1zuwA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 VAL A  93
PRO A   5
ILE A  22
VAL A   8
ILE A  32
None
1.25A 4eb6B-1zuwA:
undetectable
4eb6C-1zuwA:
undetectable
4eb6B-1zuwA:
20.94
4eb6C-1zuwA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 8 LEU A 226
PRO A  92
VAL A   8
GLY A   7
None
0.90A 4klrB-1zuwA:
2.8
4klrB-1zuwA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 ASP A 163
ILE A 165
ARG A 197
VAL A 203
ILE A 178
None
0.94A 4q5mA-1zuwA:
undetectable
4q5mA-1zuwA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.48A 4qvlV-1zuwA:
undetectable
4qvlb-1zuwA:
undetectable
4qvlV-1zuwA:
21.83
4qvlb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.47A 4qvlH-1zuwA:
undetectable
4qvlN-1zuwA:
undetectable
4qvlH-1zuwA:
21.83
4qvlN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.45A 4qvmV-1zuwA:
undetectable
4qvmb-1zuwA:
undetectable
4qvmV-1zuwA:
21.83
4qvmb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.44A 4qvmH-1zuwA:
undetectable
4qvmN-1zuwA:
undetectable
4qvmH-1zuwA:
21.83
4qvmN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.47A 4qvpV-1zuwA:
undetectable
4qvpb-1zuwA:
undetectable
4qvpV-1zuwA:
21.83
4qvpb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.46A 4qvpH-1zuwA:
undetectable
4qvpN-1zuwA:
undetectable
4qvpH-1zuwA:
21.83
4qvpN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.46A 4qvqV-1zuwA:
undetectable
4qvqb-1zuwA:
undetectable
4qvqV-1zuwA:
21.83
4qvqb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.45A 4qvqH-1zuwA:
undetectable
4qvqN-1zuwA:
undetectable
4qvqH-1zuwA:
21.83
4qvqN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.44A 4qvwV-1zuwA:
undetectable
4qvwb-1zuwA:
undetectable
4qvwV-1zuwA:
21.83
4qvwb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.44A 4qvwH-1zuwA:
undetectable
4qvwN-1zuwA:
undetectable
4qvwH-1zuwA:
21.83
4qvwN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.47A 4qw1V-1zuwA:
undetectable
4qw1b-1zuwA:
undetectable
4qw1V-1zuwA:
21.83
4qw1b-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.45A 4qw1H-1zuwA:
undetectable
4qw1N-1zuwA:
undetectable
4qw1H-1zuwA:
21.83
4qw1N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.46A 4qw3V-1zuwA:
undetectable
4qw3b-1zuwA:
undetectable
4qw3V-1zuwA:
21.83
4qw3b-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.45A 4qw3H-1zuwA:
undetectable
4qw3N-1zuwA:
undetectable
4qw3H-1zuwA:
21.83
4qw3N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.49A 4qwuV-1zuwA:
undetectable
4qwub-1zuwA:
undetectable
4qwuV-1zuwA:
21.83
4qwub-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.49A 4qwuH-1zuwA:
undetectable
4qwuN-1zuwA:
undetectable
4qwuH-1zuwA:
21.83
4qwuN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.45A 5cz7H-1zuwA:
undetectable
5cz7N-1zuwA:
undetectable
5cz7H-1zuwA:
21.83
5cz7N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.47A 5d0xV-1zuwA:
undetectable
5d0xb-1zuwA:
undetectable
5d0xV-1zuwA:
21.83
5d0xb-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.46A 5d0xH-1zuwA:
undetectable
5d0xN-1zuwA:
undetectable
5d0xH-1zuwA:
21.83
5d0xN-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5eevA-1zuwA:
undetectable
5eevB-1zuwA:
undetectable
5eevA-1zuwA:
13.97
5eevB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5eewA-1zuwA:
undetectable
5eewB-1zuwA:
undetectable
5eewA-1zuwA:
13.97
5eewB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5eexA-1zuwA:
undetectable
5eexB-1zuwA:
undetectable
5eexA-1zuwA:
13.97
5eexB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5eeyA-1zuwA:
undetectable
5eeyB-1zuwA:
undetectable
5eeyA-1zuwA:
13.97
5eeyB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5eezA-1zuwA:
undetectable
5eezB-1zuwA:
undetectable
5eezA-1zuwA:
13.97
5eezB-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5ef0A-1zuwA:
undetectable
5ef0B-1zuwA:
undetectable
5ef0A-1zuwA:
13.97
5ef0B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5ef1A-1zuwA:
undetectable
5ef1B-1zuwA:
undetectable
5ef1A-1zuwA:
13.97
5ef1B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.09A 5ef2A-1zuwA:
undetectable
5ef2B-1zuwA:
undetectable
5ef2A-1zuwA:
13.97
5ef2B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 GLY A 184
THR A 186
HIS A 187
THR A 121
THR A 118
None
DGL  A1301 (-3.1A)
DGL  A1301 (-4.2A)
None
DGL  A1301 (-3.5A)
1.10A 5ef3A-1zuwA:
undetectable
5ef3B-1zuwA:
undetectable
5ef3A-1zuwA:
13.97
5ef3B-1zuwA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
4 / 7 GLY A 209
VAL A   8
ILE A  72
VAL A  71
None
0.78A 5ik1A-1zuwA:
undetectable
5ik1A-1zuwA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.48A 5l66V-1zuwA:
undetectable
5l66b-1zuwA:
undetectable
5l66V-1zuwA:
21.83
5l66b-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 11 SER A 208
THR A  76
THR A  78
GLY A  14
THR A  17
None
DGL  A1301 (-3.7A)
None
None
None
1.47A 5l66H-1zuwA:
undetectable
5l66N-1zuwA:
undetectable
5l66H-1zuwA:
21.83
5l66N-1zuwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 10 PRO A   5
LEU A  70
ILE A  72
ALA A  77
VAL A  34
None
1.34A 5m0oA-1zuwA:
undetectable
5m0oA-1zuwA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)
1zuw GLUTAMATE RACEMASE 1
(Bacillus
subtilis)
5 / 12 GLY A 184
ILE A 182
THR A 212
VAL A  18
LEU A 131
None
1.34A 5nz0A-1zuwA:
0.0
5nz0A-1zuwA:
24.01