SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.96A 1v54N-1zv4X:
undetectable
1v54W-1zv4X:
undetectable		 1v54N-1zv4X:
13.67
1v54W-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.93A 1v55A-1zv4X:
undetectable
1v55J-1zv4X:
undetectable		 1v55A-1zv4X:
13.67
1v55J-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.88A 1v55N-1zv4X:
undetectable
1v55W-1zv4X:
undetectable		 1v55N-1zv4X:
13.67
1v55W-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.97A 2dyrN-1zv4X:
undetectable
2dyrW-1zv4X:
undetectable		 2dyrN-1zv4X:
13.67
2dyrW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.87A 2eijN-1zv4X:
0.0
2eijW-1zv4X:
undetectable		 2eijN-1zv4X:
13.67
2eijW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.88A 2eikN-1zv4X:
0.0
2eikW-1zv4X:
undetectable		 2eikN-1zv4X:
13.67
2eikW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.90A 2eilN-1zv4X:
0.0
2eilW-1zv4X:
undetectable		 2eilN-1zv4X:
13.67
2eilW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		3 / 3 LEU X 151
LEU X 163
PHE X 113
 None
 0.64A 2pgrA-1zv4X:
undetectable		 2pgrA-1zv4X:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 6 SER X 107
ARG X  99
PHE X  98
PHE X  85
 None
 1.17A 2qeiA-1zv4X:
2.0		 2qeiA-1zv4X:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.92A 3abkA-1zv4X:
undetectable
3abkJ-1zv4X:
undetectable		 3abkA-1zv4X:
13.67
3abkJ-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.88A 3abmN-1zv4X:
undetectable
3abmW-1zv4X:
undetectable		 3abmN-1zv4X:
13.67
3abmW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.90A 3asnN-1zv4X:
undetectable
3asnW-1zv4X:
undetectable		 3asnN-1zv4X:
13.67
3asnW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.88A 3asoN-1zv4X:
undetectable
3asoW-1zv4X:
undetectable		 3asoN-1zv4X:
13.67
3asoW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		3 / 3 ASN X 160
GLU X 157
ARG X 156
 None
 0.80A 3wxoA-1zv4X:
undetectable		 3wxoA-1zv4X:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		5 / 10 LEU X 112
MET X 182
PHE X  98
GLU X 108
PHE X  85
 None
 1.33A 4la0A-1zv4X:
undetectable		 4la0A-1zv4X:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.94A 5b1aA-1zv4X:
undetectable
5b1aJ-1zv4X:
undetectable		 5b1aA-1zv4X:
13.67
5b1aJ-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.84A 5b1bA-1zv4X:
2.2
5b1bJ-1zv4X:
undetectable		 5b1bA-1zv4X:
13.67
5b1bJ-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.98A 5b3sA-1zv4X:
undetectable
5b3sJ-1zv4X:
undetectable		 5b3sA-1zv4X:
13.67
5b3sJ-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 159
VAL X 155
GLN X 175
GLU X 172
 None
 0.98A 5dqyA-1zv4X:
undetectable		 5dqyA-1zv4X:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.90A 5iy5A-1zv4X:
1.4
5iy5J-1zv4X:
undetectable		 5iy5A-1zv4X:
13.67
5iy5J-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.93A 5xdqN-1zv4X:
undetectable
5xdqW-1zv4X:
undetectable		 5xdqN-1zv4X:
13.67
5xdqW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.93A 5xdxN-1zv4X:
0.0
5xdxW-1zv4X:
undetectable		 5xdxN-1zv4X:
13.67
5xdxW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.97A 5zcpA-1zv4X:
undetectable
5zcpJ-1zv4X:
undetectable		 5zcpA-1zv4X:
13.67
5zcpJ-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.92A 5zcpN-1zv4X:
undetectable
5zcpW-1zv4X:
undetectable		 5zcpN-1zv4X:
13.67
5zcpW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 7 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.95A 5zcqA-1zv4X:
undetectable
5zcqJ-1zv4X:
undetectable		 5zcqA-1zv4X:
13.67
5zcqJ-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 8 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.82A 5zcqN-1zv4X:
undetectable
5zcqW-1zv4X:
undetectable		 5zcqN-1zv4X:
13.67
5zcqW-1zv4X:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1zv4 REGULATOR OF
G-PROTEIN SIGNALING
17
(Homo
sapiens) 		4 / 5 ILE X 178
LEU X 181
ARG X  95
LEU X 102
 None
 0.90A 6nmpN-1zv4X:
1.7
6nmpW-1zv4X:
undetectable		 6nmpN-1zv4X:
13.67
6nmpW-1zv4X:
18.79