SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zvf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  29
ILE A   9
ARG A 101
GLY A  40
 None
 0.89A 2du8A-1zvfA:
undetectable		 2du8A-1zvfA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  29
ILE A   9
ARG A 101
GLY A  40
 None
 0.95A 2du8B-1zvfA:
undetectable		 2du8B-1zvfA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 6 THR A  72
GLU A  71
PHE A  78
ILE A  79
 None
 1.32A 2w98B-1zvfA:
undetectable		 2w98B-1zvfA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 114
GLY A  32
GLY A 144
ASN A  26
 None
 1.00A 3v3nB-1zvfA:
undetectable		 3v3nB-1zvfA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 114
GLY A  32
GLY A 144
ASN A  26
 None
 1.00A 3v3nC-1zvfA:
undetectable		 3v3nC-1zvfA:
17.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		6 / 7 HIS A  49
GLU A  55
HIS A  97
PRO A  99
VAL A 109
GLU A 111
 NI  A 201 (-3.2A)
NI  A 201 (-2.0A)
NI  A 201 (-3.2A)
None
None
NI  A 201 ( 4.6A)
 0.51A 4hvrA-1zvfA:
23.1		 4hvrA-1zvfA:
37.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 120
HIS A  49
LYS A 121
 None
NI  A 201 (-3.2A)
None
 0.77A 4qzuD-1zvfA:
undetectable		 4qzuD-1zvfA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 6 LYS A  67
LEU A  66
PHE A  57
LEU A  91
 None
 1.16A 5x19P-1zvfA:
undetectable		 5x19P-1zvfA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 120
ASN A  94
LEU A  91
PHE A  57
 None
 1.20A 6ekuA-1zvfA:
undetectable		 6ekuA-1zvfA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 130
LYS A  67
TYR A  48
 None
 1.16A 6gnaA-1zvfA:
undetectable		 6gnaA-1zvfA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1zvf 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 130
LYS A  67
TYR A  48
 None
 1.16A 6gnbA-1zvfA:
undetectable		 6gnbA-1zvfA:
21.65