SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C2B_A_SAMA500_0 (THREONINE SYNTHASE 1, CHLOROPLASTIC)	1zvh	IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN (Camelus dromedarius)	5 / 10	TRP A 36 GLY A 8 SER A 7 LEU A 93 GLN A 120	None	1.48A	2c2bA-1zvhA: 0.0 2c2bB-1zvhA: 0.0	2c2bA-1zvhA: 13.17 2c2bB-1zvhA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_A_ASDA1224_1 (GLUTATHIONE S-TRANSFERASE A3)	1zvh	IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN (Camelus dromedarius)	4 / 7	PHE A 37 ALA A 50 LEU A 34 ALA A 97	None	1.11A	2vcvA-1zvhA: undetectable	2vcvA-1zvhA: 17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	1zvh	IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN (Camelus dromedarius)	4 / 5	TYR A 94 LEU A 81 LEU A 86 ARG A 67	None	1.27A	4em2A-1zvhA: undetectable	4em2A-1zvhA: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESL_A_1YNA701_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1zvh	IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN (Camelus dromedarius)	4 / 5	ALA A 61 TYR A 60 GLY A 26 LEU A 72	None	1.02A	5eslA-1zvhA: undetectable	5eslA-1zvhA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QGB_A_BEZA701_0 (MONO(2-HYDROXYETHYL) TEREPHTHALATE HYDROLASE)	1zvh	IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN (Camelus dromedarius)	5 / 11	GLY A 111 SER A 109 ALA A 50 ALA A 97 PHE A 37	None	1.49A	6qgbA-1zvhA: undetectable	6qgbA-1zvhA: 15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6QGB_E_BEZE701_0 (MONO(2-HYDROXYETHYL) TEREPHTHALATE HYDROLASE)	1zvh	IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN (Camelus dromedarius)	5 / 11	GLY A 111 SER A 109 ALA A 50 ALA A 97 PHE A 37	None	1.48A	6qgbE-1zvhA: undetectable	6qgbE-1zvhA: 15.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2C2B_A_SAMA500_0","THREONINE SYNTHASE 1, CHLOROPLASTIC","1zvh","IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN","Camelus dromedarius",5,"TRP A  36;GLY A   8;SER A   7;LEU A  93;GLN A 120","None","1.48A","2c2bA-1zvhA:0.0;2c2bB-1zvhA:0.0","2c2bA-1zvhA:13.17;2c2bB-1zvhA:13.17"],["2VCV_A_ASDA1224_1","GLUTATHIONE S-TRANSFERASE A3","1zvh","IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN","Camelus dromedarius",4,"PHE A  37;ALA A  50;LEU A  34;ALA A  97","None","1.11A","2vcvA-1zvhA:undetectable","2vcvA-1zvhA:17.33"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","1zvh","IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN","Camelus dromedarius",4,"TYR A  94;LEU A  81;LEU A  86;ARG A  67","None","1.27A","4em2A-1zvhA:undetectable","4em2A-1zvhA:17.03"],["5ESL_A_1YNA701_2","LANOSTEROL 14-ALPHA DEMETHYLASE","1zvh","IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN","Camelus dromedarius",4,"ALA A  61;TYR A  60;GLY A  26;LEU A  72","None","1.02A","5eslA-1zvhA:undetectable","5eslA-1zvhA:12.99"],["6QGB_A_BEZA701_0","MONO(2-HYDROXYETHYL) TEREPHTHALATE HYDROLASE","1zvh","IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN","Camelus dromedarius",5,"GLY A 111;SER A 109;ALA A  50;ALA A  97;PHE A  37","None","1.49A","6qgbA-1zvhA:undetectable","6qgbA-1zvhA:15.18"],["6QGB_E_BEZE701_0","MONO(2-HYDROXYETHYL) TEREPHTHALATE HYDROLASE","1zvh","IMMUNOGLOBULIN HEAVY CHAIN ANTIBODY VARIABLE DOMAIN","Camelus dromedarius",5,"GLY A 111;SER A 109;ALA A  50;ALA A  97;PHE A  37","None","1.48A","6qgbE-1zvhA:undetectable","6qgbE-1zvhA:15.18"]]