SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1zvs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		3 / 3 ASN A  86
ALA A 139
ASN A 142
 None
 0.81A 1n4fA-1zvsA:
undetectable		 1n4fA-1zvsA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		3 / 3 GLU A 128
GLU A 161
LEU A 103
 None
 0.65A 1v8bA-1zvsA:
undetectable		 1v8bA-1zvsA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		3 / 3 GLU A 128
GLU A 161
LEU A 103
 None
 0.70A 1v8bB-1zvsA:
undetectable		 1v8bB-1zvsA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		3 / 3 TRP A 167
GLU A  63
TYR A  59
 None
 1.01A 2a3aA-1zvsA:
undetectable		 2a3aA-1zvsA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		5 / 10 ALA A  49
THR A  31
LEU A 179
MET A   5
VAL A  28
 None
 1.39A 2wuzA-1zvsA:
undetectable		 2wuzA-1zvsA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		5 / 10 ALA A  49
THR A  31
LEU A 179
MET A   5
VAL A  28
 None
 1.36A 2wuzB-1zvsA:
undetectable		 2wuzB-1zvsA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		5 / 9 GLU A 254
THR A 190
VAL A 189
LEU A 201
ALA A 199
 None
 1.45A 3ax7B-1zvsA:
undetectable		 3ax7B-1zvsA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		4 / 7 ARG A 202
ALA A 246
VAL A 194
VAL A 248
 None
 0.74A 3o14A-1zvsA:
undetectable		 3o14A-1zvsA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.44A 5m5kA-1zvsA:
undetectable		 5m5kA-1zvsA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.41A 5m66B-1zvsA:
undetectable		 5m66B-1zvsA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 1zvs MHC CLASS I ANTIGEN
(Macaca
mulatta) 		4 / 4 GLN A 218
THR A 216
THR A 187
LEU A 266
 None
 1.41A 6f3mB-1zvsA:
undetectable		 6f3mB-1zvsA:
21.91